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Share-based Payments
6 Months Ended
Jun. 30, 2022
Share-based Payment Arrangement [Abstract]  
Share-based Payments
Share-based Compensation Expense
The following table summarizes share-based compensation expense included in our condensed consolidated statements of income:
For the Three Months Ended June 30,For the Six Months Ended June 30,
(In millions)2022202120222021
Research and development $22.4 $19.1 $48.1 $52.7 
Selling, general and administrative36.7 40.3 82.8 85.2 
Subtotal59.1 59.4 130.9 137.9 
Capitalized share-based compensation costs (2.3)(1.7)(5.1)(4.3)
Share-based compensation expense included in total cost and expense56.8 57.7 125.8 133.6 
Income tax effect(10.2)(10.9)(23.0)(24.9)
Share-based compensation expense included in net income attributable to Biogen Inc.$46.6 $46.8 $102.8 $108.7 
The following table summarizes share-based compensation expense associated with each of our share-based compensation programs:
For the Three Months Ended June 30,For the Six Months Ended June 30,
(In millions)2022202120222021
Market stock units$1.5 $9.3 $7.4 $25.8 
Time-vested restricted stock units50.4 40.4 101.7 83.2 
Performance stock units settled in stock3.3 3.0 11.6 9.3 
Performance stock units settled in cash1.1 3.4 2.5 9.4 
Employee stock purchase plan2.8 3.3 7.7 10.2 
Subtotal59.1 59.4 130.9 137.9 
Capitalized share-based compensation costs(2.3)(1.7)(5.1)(4.3)
Share-based compensation expense included in total cost and expense$56.8 $57.7 $125.8 $133.6 
We estimate the fair value of our obligations associated with our performance stock units settled in cash at the end of each reporting period through expected settlement. Cumulative adjustments to these obligations are recognized each quarter to reflect changes in the stock price and estimated outcome of the performance-related conditions.