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Collaborative and Other Relationships - Equity Method Investments (Details)
$ in Millions, ₩ in Billions
1 Months Ended 3 Months Ended
Jan. 31, 2022
USD ($)
Mar. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Mar. 31, 2020
USD ($)
Mar. 31, 2022
KRW (₩)
Dec. 31, 2021
KRW (₩)
Jan. 31, 2020
USD ($)
Nov. 07, 2018
USD ($)
Schedule of Equity Method Investments [Line Items]                    
Income (loss) from equity method investments   $ (3.3)     $ (18.2)          
Collaboration profit (loss) sharing   $ (117.3)     68.5          
Samsung Bioepis                    
Schedule of Equity Method Investments [Line Items]                    
Percentage of stake in entity maximum   49.90%         49.90%      
Amortization of basis differences                   $ 675.0
Loss recorded on Samsung Bioepis joint venture   $ 3.3     18.2          
Income (loss) from equity method investments   4.0     11.0          
Investment in Samsung Bioepis   586.4 $ 599.9       ₩ 709.4 ₩ 713.3    
Collaboration profit (loss) sharing   64.4     68.5          
Eisai                    
Schedule of Equity Method Investments [Line Items]                    
Income (loss) from equity method investments   181.7                
Due to Related Parties   36.5 46.5              
Eisai | ADUHELM                    
Schedule of Equity Method Investments [Line Items]                    
Income (loss) from equity method investments   $ 160.0 59.0 $ 45.0 $ 45.0          
Samsung Bioepis                    
Schedule of Equity Method Investments [Line Items]                    
Proceeds from Divestiture of Interest in Joint Venture $ 1,000.0                  
Payables To Divestiture Of Interest In Joint Venture 1,300.0                  
Equity Method Investments, Expected Profit Share   50.00%                
Upfront and milestone payments made to collaborative partner           $ 100.0        
Research and development expense           $ 63.0        
Prepaid research and development expenses                 $ 37.0  
Accrued milestone payments   $ 15.0                
Estimated additional payments upon achievement of development and commercial milestones 50.0 180.0                
Contract Option Exercise Fee   60.0                
Due to Related Parties   $ 102.5 $ 148.7              
Samsung Bioepis | Payment Due At First Anniversary                    
Schedule of Equity Method Investments [Line Items]                    
Payables To Divestiture Of Interest In Joint Venture 812.5                  
Samsung Bioepis | Payment Due At Second Anniversary                    
Schedule of Equity Method Investments [Line Items]                    
Payables To Divestiture Of Interest In Joint Venture $ 437.5                  
Inventory | Samsung Bioepis                    
Schedule of Equity Method Investments [Line Items]                    
Equity method investment basis difference amortization period   1 year 6 months                
Developed technology | Samsung Bioepis                    
Schedule of Equity Method Investments [Line Items]                    
Equity method investment basis difference amortization period   15 years