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Other Consolidated Financial Statement (Details Textual) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Net gains recognized on the increase in fair value of equity securities $ (190.9) $ (442.3)  
Net gains (losses) realized during the period on equity securities 0.2 $ 6.2  
Other long-term liabilities 1,287.9   $ 1,320.5
Accrued income taxes 640.5   $ 664.5
Ionis, Sangamo, Denali and Sage      
Net gains recognized on the increase in fair value of equity securities $ 205.5