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Fair Value Measurements (Tables)
 3 Months Ended
Mar. 31, 2022
Fair Value Disclosures [Abstract]  
Summary of assets and liabilities recorded at fair value
The tables below present information about our assets and liabilities that are regularly measured and carried at fair value and indicate the level within the fair value hierarchy of the valuation techniques we utilized to determine such fair value:
As of March 31, 2022
(In millions)TotalQuoted Prices
in Active
Markets
(Level 1)		Significant Other
Observable Inputs
(Level 2)		Significant
Unobservable
Inputs
(Level 3)
Assets:
Cash equivalents$1,283.7 $— $1,283.7 $— 
Marketable debt securities:
Corporate debt securities1,579.4 — 1,579.4 — 
Government securities1,252.7 — 1,252.7 — 
Mortgage and other asset backed securities171.9 — 171.9 — 
Marketable equity securities860.3 607.0 253.3 — 
Derivative contracts97.2 — 97.2 — 
Plan assets for deferred compensation35.8 — 35.8 — 
Total$5,281.0 $607.0 $4,674.0 $— 
Liabilities:
Derivative contracts$12.5 $— $12.5 $— 
Contingent consideration obligations202.0 — — 202.0 
Total$214.5 $— $12.5 $202.0 
As of December 31, 2021
(In millions)TotalQuoted Prices
in Active
Markets
(Level 1)		Significant Other
Observable Inputs
(Level 2)		Significant
Unobservable
Inputs
(Level 3)
Assets:
Cash equivalents$1,632.2 $— $1,632.2 $— 
Marketable debt securities:
Corporate debt securities1,108.2 — 1,108.2 — 
Government securities1,192.7 — 1,192.7 — 
Mortgage and other asset backed securities132.2 — 132.2 — 
Marketable equity securities1,048.5 181.7 866.8 — 
Derivative contracts80.9 — 80.9 — 
Plan assets for deferred compensation33.4 — 33.4 — 
Total$5,228.1 $181.7 $5,046.4 $— 
Liabilities:
Derivative contracts$10.8 $— $10.8 $— 
Contingent consideration obligations209.1 — — 209.1 
Total$219.9 $— $10.8 $209.1 
Summary of fair and carrying value of debt instruments
The fair and carrying values of our debt instruments, which are Level 2 liabilities, are summarized as follows:
 As of March 31, 2022As of December 31, 2021
(In millions)Fair
Value		Carrying
Value		Fair
Value		Carrying
Value
3.625% Senior Notes due September 15, 2022$1,008.7 $999.5 $1,020.0 $999.1 
4.050% Senior Notes due September 15, 20251,797.6 1,743.4 1,895.2 1,742.9 
2.250% Senior Notes due May 1, 20301,341.6 1,492.2 1,475.9 1,492.0 
5.200% Senior Notes due September 15, 20451,240.0 1,100.0 1,463.0 1,099.9 
3.150% Senior Notes due May 1, 20501,225.3 1,473.3 1,457.7 1,473.2 
3.250% Senior Notes due February 15, 2051581.8 466.8 692.9 466.0 
Total$7,195.0 $7,275.2 $8,004.7 $7,273.1 
Fair value of contingent consideration obligations The following table provides a roll forward of the fair values of our contingent consideration obligations, which includes Level 3 measurements:
 For the Three Months Ended March 31,
(In millions)20222021
Fair value, beginning of period$209.1 $259.8 
Changes in fair value(7.1)(33.8)
Fair value, end of period$202.0 $226.0