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Property, Plant and Equipment - Narrative (Details)
ft² in Thousands, $ in Millions
12 Months Ended
Dec. 31, 2021
USD ($)
ft²
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jun. 30, 2021
USD ($)
Property, Plant and Equipment [Line Items]        
Depreciation expense $ 235.3 $ 201.9 $ 190.6  
Interest costs capitalized 36.3 65.2 $ 68.8  
Construction in progress 770.3 1,950.8    
Property, plant and equipment, gross 5,423.0 5,193.8    
Solothurn, Switzerland        
Property, Plant and Equipment [Line Items]        
Construction in progress $ 677.0 $ 1,800.0    
Property, plant and equipment, gross       $ 1,200.0
Biologics Manufacturing | Solothurn, Switzerland        
Property, Plant and Equipment [Line Items]        
Number of square feet | ft² 393      
Warehouse, Utilities and Support Space | Solothurn, Switzerland        
Property, Plant and Equipment [Line Items]        
Number of square feet | ft² 290      
Administrative Space | Solothurn, Switzerland        
Property, Plant and Equipment [Line Items]        
Number of square feet | ft² 51