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Derivative Instruments - Narrative (Details)
$ in Millions, ₩ in Billions
1 Months Ended 12 Months Ended
Nov. 30, 2018
KRW (₩)
Nov. 30, 2018
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jun. 30, 2018
May 31, 2018
Feb. 29, 2012
Derivatives, Fair Value [Line Items]                
Range of durations of foreign currency forward contracts     15 months          
Net gains (losses) of other income (expense) related to foreign currency forward contracts     $ (43.3) $ 30.1 $ (5.9)      
Net investment hedge                
Derivatives, Fair Value [Line Items]                
Forward contracts duration     10 months          
Derivative qualifying as hedge gain (loss), excluded component, after tax     $ (3.6) 0.2        
Samsung Bioepis                
Derivatives, Fair Value [Line Items]                
Ownership percentage before additional purchase transaction             5.00%  
Ownership percentage     49.90%     49.90%   15.00%
Payments to increase investment in Samsung Bioepis ₩ 759.5 $ 676.6            
Designated as Hedging Instrument                
Derivatives, Fair Value [Line Items]                
Derivative, notional amount     $ 2,126.8 3,229.7        
Not designated as hedging instrument                
Derivatives, Fair Value [Line Items]                
Derivative, notional amount     1,268.0 1,158.0        
Foreign Exchange Forward                
Derivatives, Fair Value [Line Items]                
Unrealized gain (loss) on derivative instruments     53.8 (212.5) $ 0.5      
Foreign Exchange Forward | Net investment hedge                
Derivatives, Fair Value [Line Items]                
Unrealized gain (loss) on derivative instruments     10.6 (21.2)        
Interest rate swap | Interest Expense                
Derivatives, Fair Value [Line Items]                
Gain (loss) on derivative instruments, net, pretax       $ 3.3        
Interest rate swap | Designated as Hedging Instrument                
Derivatives, Fair Value [Line Items]                
Derivative, notional amount     $ 675.0          
Short-term derivative                
Derivatives, Fair Value [Line Items]                
Range of durations of foreign currency forward contracts     12 months          
Unrealized gain (loss) on derivative instruments     $ 48.2          
Minimum                
Derivatives, Fair Value [Line Items]                
Range of durations of foreign currency forward contracts     1 month 1 month        
Maximum                
Derivatives, Fair Value [Line Items]                
Range of durations of foreign currency forward contracts     15 months 24 months