Revenues - Other Revenues (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Disaggregation of Revenue [Line Items]
Total product revenue	$ 10,981.7	$ 13,444.6	$ 14,377.9
Royalty
Disaggregation of Revenue [Line Items]
Total product revenue	27.9	33.9	17.0
Other corporate
Disaggregation of Revenue [Line Items]
Total product revenue	427.7	719.1	584.5
Total other revenue
Disaggregation of Revenue [Line Items]
Total product revenue	476.3	774.6	707.7
Collaborative Arrangement | Samsung Bioepis
Disaggregation of Revenue [Line Items]
Total product revenue	20.7	20.9	106.2
Collaborative Arrangement | Other Relationships
Disaggregation of Revenue [Line Items]
Total product revenue	$ 0.0	$ 0.7	$ 0.0