Intangible Assets and Goodwill (Tables)

12 Months Ended

Dec. 31, 2021

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible assets

Intangible assets, net of accumulated amortization, impairment charges and adjustments are summarized as follows:

		As of December 31, 2021						As of December 31, 2020
(In millions)	Estimated Life	Cost		Accumulated Amortization		Net		Cost		Accumulated Amortization		Net
Completed technology	4-28 years	$	7,413.1	$	(5,388.5)	$	2,024.6	$	7,394.3	$	(5,136.5)	$	2,257.8
In-process research and development	Indefinite until commercialization	132.7		—		132.7		762.5		—		762.5
Trademarks and trade names	Indefinite	64.0		—		64.0		64.0		—		64.0
Total intangible assets		$	7,609.8	$	(5,388.5)	$	2,221.3	$	8,220.8	$	(5,136.5)	$	3,084.3

Estimated future amortization of intangible assets

The estimated future amortization of finite-lived intangible assets for the next five years is expected to be as follows:

(In millions)	As of December 31, 2021
2022	$	255.0
2023	210.0
2024	195.0
2025	195.0
2026	180.0

Summary of roll forward of the changes in goodwill

The following table provides a roll forward of the changes in our goodwill balance:

	As of December 31,
(In millions)	2021		2020
Goodwill, beginning of year	$	5,762.1	$	5,757.8
Other	(1.0)		4.3
Goodwill, end of year	$	5,761.1	$	5,762.1