Collaborative and Other Relationships - Summary of Activity Related to Sage Therapeutics (Details) - Sage Therapeutics $ in Millions	12 Months Ended
	Dec. 31, 2021 USD ($)
Research and development
Collaborative arrangements and non-collaborative arrangement transactions
Expense incurred by the collaboration	$ 167.7
Expense reflected within statements of income	83.8
Selling, general and administrative
Collaborative arrangements and non-collaborative arrangement transactions
Expense incurred by the collaboration	36.4
Expense reflected within statements of income	$ 18.2