Collaborative and Other Relationships - Pretax Profit Sharing Formula (Details) - GAZYVA	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Collaborative arrangements and non-collaborative arrangement transactions
After First GAZYVA Threshold Date until Second GAZYVA Threshold Date	37.50%	37.50%	37.50%
After Second GAZYVA Threshold Date	35.00%

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration