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Income Taxes - Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
Statutory rate 21.00% 21.00% 21.00%
State taxes 0.80% 0.70% 0.80%
Taxes on foreign earnings (10.50%) (3.30%) (4.50%)
Tax credits (3.80%) (1.20%) (1.10%)
Purchased intangible assets (1.60%) 0.70% 0.40%
Divestiture of Denmark manufacturing operations 0.00% (0.40%) 1.00%
Internal reorganization of certain intellectual property rights 0.00% 0.00% (2.10%)
TECFIDERA impairment 0.00% 1.80% 0.00%
GILTI 1.30% 1.30% 1.50%
Swiss tax reform 0.00% 0.00% (0.80%)
Neurimmune tax impacts (5.30%) (0.10%) 0.00%
Other 1.10% (0.80%) 0.10%
Effective tax rate 3.00% 19.70% 16.30%