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Derivative Instruments (Details)
$ in Millions, ₩ in Billions
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Nov. 30, 2018
USD ($)
Nov. 30, 2018
KRW (₩)
Sep. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Sep. 30, 2020
USD ($)
Mar. 31, 2020
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2020
USD ($)
Derivatives [Line Items]                  
Gain/Loss on fair value of foreign currency forward contracts     $ 21.9       $ 21.9   $ (212.5)
Gain (loss) on foreign currency derivative instruments not designated as hedging instruments     (13.5)   $ 7.8   (26.1) $ 13.7  
Unrealized Gross Losses on Foreign Currency Derivatives, Net, before Tax     38.4       38.4    
Unrealized Gross Gains on Foreign Currency Derivatives, Net, before Tax     16.5       16.5    
Gains (losses) on net investment hedges     15.1   (11.3)   35.2 5.5  
Ionis, Sangamo, Denali and Sage                  
Derivatives [Line Items]                  
Net losses recognized on the decrease in fair value of equity securities             $ 709.1    
Minimum                  
Derivatives [Line Items]                  
Range of durations of foreign currency forward contracts             1 month   1 month
Maximum                  
Derivatives [Line Items]                  
Range of durations of foreign currency forward contracts             18 months   24 months
Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     1,400.6       $ 1,400.6   $ 1,158.0
Other current assets | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     34.5       34.5   0.0
Other current assets | Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     6.1       6.1   20.5
Other noncurrent assets | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     14.1       14.1   0.0
Accrued expenses and other | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative liability, fair value     11.8       11.8   157.1
Accrued expenses and other | Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative liability, fair value     15.9       15.9   4.7
Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     2,080.8       2,080.8   3,229.7
Interest rate swap | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     675.0       675.0    
Cash Flow Hedging [Member] | Foreign exchange contract | Other long-term liabilities                  
Derivatives [Line Items]                  
Derivative liability, fair value     0.0       $ 0.0   35.7
Net Investment Hedging                  
Derivatives [Line Items]                  
Remaining duration of Net Investment Hedges             1 month    
Unrealized gain (loss) on net investment hedges in AOCI       $ 21.2     $ 25.0    
Derivative qualifying as net investment hedge, excluded component     0.0       0.0   0.2
Gains (losses) on net investment hedges     24.9   (10.4)   46.1 5.0  
Gains (losses) on net investment hedge, excluded component     0.0   (0.2)   (1.1) 3.1  
Net Investment Hedging | Foreign exchange contract | Other current assets                  
Derivatives [Line Items]                  
Derivative asset, fair value     25.3       25.3   0.0
Net Investment Hedging | Foreign exchange contract | Accrued expenses and other                  
Derivatives [Line Items]                  
Derivative liability, fair value     0.0       0.0   19.7
Interest Expense | Interest rate swap                  
Derivatives [Line Items]                  
Gain on interest rate swap             3.3    
Revenue | Foreign exchange contract                  
Derivatives [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax     (14.9)   (9.1)   (68.7) 41.6  
Revenue | Cash flows, revenue | Foreign exchange contract                  
Derivatives [Line Items]                  
Gain on interest rate swap     (0.7)   (8.7)   (4.5) (1.0)  
Operating expense | Foreign exchange contract                  
Derivatives [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax     (0.3)   1.5   (0.3) 1.4  
Operating expense | Cash flows, operating expenses | Foreign exchange contract                  
Derivatives [Line Items]                  
Gain on interest rate swap     0.0   0.4   (0.4) (0.7)  
Other income (expense) | Net Investment Hedging                  
Derivatives [Line Items]                  
Gain (loss) recognized in net income, excluded component     0.0   $ 0.9   0.1 $ 2.6  
Euro | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     1,901.5       1,901.5   2,979.1
British pound | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     30.1       30.1   0.0
Swiss franc | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     63.6       63.6   250.6
Japan, Yen | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     25.2       25.2   0.0
Canadian dollar | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     $ 60.4       $ 60.4   $ 0.0
2.900% Senior Notes due 2020                  
Derivatives [Line Items]                  
Senior notes interest rate     2.90%       2.90%    
Samsung Bioepis                  
Derivatives [Line Items]                  
Percentage of stake in entity         5.00%     5.00%  
Equity Method Investment, Ownership Percentage     49.90%       49.90%    
Payments to acquire additional investment in equity method investment $ 676.6 ₩ 759.5       $ 676.6      
Short-term derivative                  
Derivatives [Line Items]                  
Gain/Loss on fair value of foreign currency forward contracts     $ 9.6       $ 9.6    
Range of durations of foreign currency forward contracts             12 months