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Other Consolidated Financial Statement Detail (Tables)
9 Months Ended
Sep. 30, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Other income (expense), net
Components of other income (expense), net, are summarized as follows:
For the Three Months Ended September 30,For the Nine Months Ended September 30,
(In millions)2021202020212020
Interest income$2.6 $6.0 $8.2 $38.0 
Interest expense(66.3)(56.3)(187.3)(166.5)
Gain (loss) on investments, net(424.5)(82.1)(707.2)(52.6)
Foreign exchange gains (losses), net(13.7)3.1 (23.1)(5.4)
Other, net(1.0)0.7 (4.0)0.4 
Total other income (expense), net$(502.9)$(128.6)$(913.4)$(186.1)
Gain (loss) on investments in equity securities
The following table summarizes our gain (loss) on investments, net that relates to our equity securities held as of September 30, 2021 and 2020:
For the Three Months Ended September 30,For the Nine Months Ended September 30,
(In millions)2021202020212020
Net gains (losses) recognized during the period on equity securities$(424.2)$(82.3)$(705.9)$(40.3)
Less: Net gains (losses) realized during the period on equity securities2.7 — 9.3 — 
Unrealized gains (losses) recognized during the period on equity securities$(426.9)$(82.3)$(715.2)$(40.3)
Accrued expenses and other
Accrued expense and other consists of the following:
(In millions)As of September 30, 2021As of December 31, 2020
Revenue-related reserves for discounts and allowances$982.4 $1,080.6 
Collaboration expense289.3 389.9 
Employee compensation and benefits299.2 333.8 
Royalties and licensing fees238.9 218.5 
Derivative liabilities27.7 181.5 
Current portion of contingent consideration obligations— 149.6 
Other713.2 791.4 
Total accrued expense and other$2,550.7 $3,145.3