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Derivative Instruments (Details)
$ in Millions, ₩ in Billions
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Nov. 30, 2018
USD ($)
Nov. 30, 2018
KRW (₩)
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Sep. 30, 2020
Dec. 31, 2020
USD ($)
Derivatives [Line Items]                  
Gain/Loss on fair value of foreign currency forward contracts     $ 53.7     $ 53.7     $ (212.5)
Gain on interest rate swap           0.0 $ 3.3    
Net gains (losses) of other income (expense) related to foreign currency forward contracts     (4.8) $ (8.3)   (12.6) 5.9    
Unrealized Gross Losses on Foreign Currency Derivatives, Net, before Tax     67.0     67.0      
Unrealized Gross Gains on Foreign Currency Derivatives, Net, before Tax     13.3     13.3      
Gains (losses) on net investment hedges     (2.3) (6.2)   20.1 16.8    
Ionis, Sangamo, Denali and Sage                  
Derivatives [Line Items]                  
Net losses recognized on the decrease in fair value of equity securities     105.8     $ 284.8      
Minimum                  
Derivatives [Line Items]                  
Range of durations of foreign currency forward contracts           1 month   1 month  
Maximum                  
Derivatives [Line Items]                  
Range of durations of foreign currency forward contracts           18 months   24 months  
Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     1,205.1     $ 1,205.1     1,158.0
Other current assets | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     9.7     9.7     0.0
Other current assets | Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     3.3     3.3     20.5
Other noncurrent assets | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative asset, fair value     7.4     7.4     0.0
Accrued expenses and other | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative liability, fair value     55.2     55.2     157.1
Accrued expenses and other | Not designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative liability, fair value     17.2     17.2     4.7
Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     2,623.5     2,623.5     3,229.7
Interest rate swap | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     675.0     675.0      
Cash Flow Hedging [Member] | Foreign exchange contract | Other long-term liabilities                  
Derivatives [Line Items]                  
Derivative liability, fair value     0.0     $ 0.0     35.7
Net Investment Hedging                  
Derivatives [Line Items]                  
Remaining duration of Net Investment Hedges           4 months      
Unrealized gain (loss) on net investment hedges in AOCI           $ 0.1     21.2
Derivative qualifying as net investment hedge, excluded component     0.1     0.1     0.2
Gains (losses) on net investment hedges     (2.5) (8.8)   21.3 15.4    
Gains (losses) on net investment hedge, excluded component     0.3 3.5   (1.1) 3.2    
Net Investment Hedging | Foreign exchange contract | Other current assets                  
Derivatives [Line Items]                  
Derivative asset, fair value     0.4     0.4     0.0
Net Investment Hedging | Foreign exchange contract | Accrued expenses and other                  
Derivatives [Line Items]                  
Derivative liability, fair value     0.0     0.0     19.7
Interest Expense | Interest rate swap                  
Derivatives [Line Items]                  
Gain on interest rate swap           3.3      
Revenue | Foreign exchange contract                  
Derivatives [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax     (30.7) 23.7   (53.8) 50.7    
Revenue | Cash flows, revenue | Foreign exchange contract                  
Derivatives [Line Items]                  
Gain on interest rate swap     (0.8) (1.6)   (3.8) 7.7    
Operating expense | Foreign exchange contract                  
Derivatives [Line Items]                  
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax     0.4 0.0   0.0 (0.1)    
Operating expense | Cash flows, operating expenses | Foreign exchange contract                  
Derivatives [Line Items]                  
Gain on interest rate swap     (0.3) (0.2)   (0.4) (1.1)    
Other income (expense) | Net Investment Hedging                  
Derivatives [Line Items]                  
Gain (loss) recognized in net income, excluded component     0.0 $ 0.8   0.1 $ 1.7    
Euro | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     2,269.2     2,269.2     2,979.1
British pound | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     62.5     62.5     0.0
Swiss franc | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     128.6     128.6     250.6
Japan, Yen | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     53.3     53.3     0.0
Canadian dollar | Foreign exchange contract | Designated as hedging instrument                  
Derivatives [Line Items]                  
Derivative, Notional Amount     $ 109.9     $ 109.9     $ 0.0
2.900% Senior Notes due 2020                  
Derivatives [Line Items]                  
Senior notes interest rate     2.90%     2.90%      
Samsung Bioepis                  
Derivatives [Line Items]                  
Percentage of stake in entity       5.00%     5.00%    
Equity Method Investment, Ownership Percentage     49.90%     49.90%      
Payments to acquire additional investment in equity method investment $ 676.6 ₩ 759.5     $ 676.6        
Short-term derivative                  
Derivatives [Line Items]                  
Gain/Loss on fair value of foreign currency forward contracts     $ 58.2     $ 58.2      
Range of durations of foreign currency forward contracts           12 months