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Other Consolidated Financial Statement Detail (Tables)
6 Months Ended
Jun. 30, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Other income (expense), net
Components of other income (expense), net, are summarized as follows:
For the Three Months Ended June 30,For the Six Months Ended June 30,
(In millions)2021202020212020
Interest income$2.7 $7.6 $5.6 $32.0 
Interest expense(56.4)(66.0)(121.1)(110.3)
Gain (loss) on investments, net153.9 106.8 (282.7)29.5 
Foreign exchange gains (losses), net(0.8)10.4 (9.4)(8.5)
Other, net(3.0)4.2 (2.9)(0.2)
Total other income (expense), net$96.4 $63.0 $(410.5)$(57.5)
Gain (loss) on investments in equity securities
The following table summarizes our gain (loss) on investments, net that relates to our equity securities held as of June 30, 2021 and 2020:
For the Three Months Ended June 30,For the Six Months Ended June 30,
(In millions)2021202020212020
Net gains (losses) recognized during the period on equity securities$154.3 $102.9 $(281.8)$42.0 
Less: Net gains (losses) realized during the period on equity securities0.4 — 6.6 — 
Unrealized gains (losses) recognized during the period on equity securities$153.9 $102.9 $(288.4)$42.0 
Accrued expenses and other
Accrued expense and other consists of the following:
(In millions)As of June 30, 2021As of December 31, 2020
Revenue-related reserves for discounts and allowances$1,042.1 $1,080.6 
Collaboration expense383.4 389.9 
Employee compensation and benefits242.5 333.8 
Royalties and licensing fees240.3 218.5 
Derivative liabilities72.4 181.5 
Current portion of contingent consideration obligations— 149.6 
Other760.3 791.4 
Total accrued expense and other$2,741.0 $3,145.3