Property, Plant and Equipment - Narrative (Details) ft² in Thousands, $ in Millions	12 Months Ended
	Dec. 31, 2020 USD ($) ft²	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Aug. 31, 2019 USD ($)
Property, Plant and Equipment [Line Items]
Depreciation expense	$ 201.9	$ 190.6	$ 269.4
Interest costs capitalized	65.2	68.8	$ 54.0
Construction in progress	1,950.8	2,084.4
Property, plant and equipment, gross	5,193.8	4,838.2
Denmark Manufacturing Operations
Property, Plant and Equipment [Line Items]
Property, plant and equipment sold to Fujifilm				$ 631.5
Denmark Manufacturing Operations | Buildings
Property, Plant and Equipment [Line Items]
Property, plant and equipment sold to Fujifilm				312.5
Denmark Manufacturing Operations | Machinery and Equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment sold to Fujifilm				$ 287.3
Solothurn
Property, Plant and Equipment [Line Items]
Construction in progress	1,800.0	$ 1,900.0
Property, plant and equipment, gross	$ 256.8
Biologics Manufacturing | Solothurn
Property, Plant and Equipment [Line Items]
Number of square feet | ft²	393
Warehouse, Utilities and Support Space | Solothurn
Property, Plant and Equipment [Line Items]
Number of square feet | ft²	290
Administrative Space | Solothurn
Property, Plant and Equipment [Line Items]
Number of square feet | ft²	51