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Other Consolidated Financial Statement (Details Textual) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2020
Mar. 31, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Class of Stock [Line Items]            
Gain (loss) on investments, net $ (82.1)   $ (4.1) $ (52.6) $ 198.9  
Other long-term liabilities 1,428.1     1,428.1   $ 1,348.9
Accrued income taxes 729.3     729.3   $ 803.3
Net gains recognized on the increase in fair value of equity securities (82.3)   $ (9.0) (40.3) 150.5  
Proceeds from sale of available-for-sale securities, equity       0.5 $ 476.0  
Tax Cuts and Jobs Act, Transition Tax for Accumulated Foreign Earnings, Income Tax Expense   $ 697.0   $ 635.0    
Ionis            
Class of Stock [Line Items]            
Net gains recognized on the increase in fair value of equity securities 66.2          
Denali Therapeutics            
Class of Stock [Line Items]            
Net gains recognized on the increase in fair value of equity securities (29.6)          
Sangamo            
Class of Stock [Line Items]            
Net gains recognized on the increase in fair value of equity securities $ 15.2