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Intangible Assets and Goodwill (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Jun. 07, 2019
Finite-Lived Intangible Assets [Line Items]            
Impairment of Intangible Assets (Excluding Goodwill)   $ 0 $ 0 $ 0    
Intangible assets            
Contingent consideration impairment $ 29,000,000.0 57,800,000 23,500,000 66,300,000    
Total intangible assets, gross 8,401,300,000   8,401,300,000   $ 8,408,800,000  
Accumulated Amortization (5,077,700,000)   (5,077,700,000)   (4,881,400,000)  
Intangible assets, net 3,323,600,000   3,323,600,000   3,527,400,000  
Amortization and impairment of acquired intangible assets 82,600,000 283,900,000 215,600,000 422,200,000    
Amortization of intangible assets (63,300,000) (68,000,000.0) (196,300,000) (206,300,000)    
Expected future amortization expense, 2019 (remaining three months) 60,000,000.0   60,000,000.0      
Expected future amortization expense, 2020 205,000,000.0   205,000,000.0      
Expected future amortization expense, 2021 215,000,000.0   215,000,000.0      
Expected future amortization expense, 2022 215,000,000.0   215,000,000.0      
Expected future amortization expense, 2023 225,000,000.0   225,000,000.0      
Expected future amortization expense, 2024 220,000,000.0   220,000,000.0      
In Process Research and Development            
Intangible assets            
Amortization and impairment of acquired intangible assets 19,300,000 $ 215,900,000 19,300,000 $ 215,900,000    
Out-licensed patents            
Intangible assets            
Cost 7,394,300,000   7,394,300,000   7,379,300,000  
Net 2,316,600,000   2,316,600,000   2,497,900,000  
Accumulated Amortization (5,077,700,000)   $ (5,077,700,000)   (4,881,400,000)  
Out-licensed patents | Minimum            
Intangible assets            
Estimated life, (in years)     13 years      
Out-licensed patents | Maximum            
Intangible assets            
Estimated life, (in years)     23 years      
Developed technology | Minimum            
Intangible assets            
Estimated life, (in years)     15 years      
Developed technology | Maximum            
Intangible assets            
Estimated life, (in years)     28 years      
Acquired and in-licensed rights and patents | Minimum            
Intangible assets            
Estimated life, (in years)     4 years      
Acquired and in-licensed rights and patents | Maximum            
Intangible assets            
Estimated life, (in years)     18 years      
In Process Research and Development            
Intangible assets            
Indefinite lived intangible assets useful life     Indefinite until commercialization      
Cost and Net 943,000,000.0   $ 943,000,000.0   965,500,000  
Accumulated Amortization 0   $ 0   0  
Trademarks and Trade Names            
Intangible assets            
Indefinite lived intangible assets useful life     Indefinite      
Cost and Net 64,000,000.0   $ 64,000,000.0   64,000,000.0  
Accumulated Amortization 0   0   $ 0  
Nightstar            
Intangible assets            
In-process research and development           $ 700,000,000.0
TGN [Member] | In Process Research and Development            
Intangible assets            
Cost and Net $ 167,600,000   $ 167,600,000