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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Other Income (Expense), Net      
Interest income $ 24.4 $ 31.2  
Interest expense (44.3) (47.9)  
Gain (loss) on investments, net (77.3) 376.4  
Foreign exchange gains (losses), net (18.9) (2.2)  
Other, net (4.4) (0.2)  
Total other income (expense), net (120.5) 357.3  
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract]      
Net gains (losses) recognized during the period on equity securities (60.9) 375.3  
Less: Net gains (losses) recognized during the period on equity securities sold during the period 0.0 0.8  
Unrealized gains (losses) recognized during the period on equity securities held as of March 31 (60.9) $ 376.1  
Accrued Expenses and Other      
Revenue-related reserves for discounts and allowances 1,281.8   $ 1,198.9
Collaboration expenses 190.3   309.1
Royalties and licensing fees 209.9   220.9
Collaboration expenses 154.6   281.6
Current portion of contingent consideration obligations 147.3   148.4
Construction in progress 27.3   78.0
Other 662.0   726.7
Total accrued expenses and other 2,437.8   2,765.8
Component of accrued expenses and other      
Accrued Expenses and Other      
Revenue-related reserves for discounts and allowances $ 1,046.4   $ 1,001.1