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Property, Plant and Equipment Property, Plant and Equipment
3 Months Ended
Mar. 31, 2020
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment Property, Plant and Equipment
Property, plant and equipment are recorded at historical cost, net of accumulated depreciation. Accumulated depreciation on property, plant and equipment was $1,636.7 million and $1,590.9 million as of March 31, 2020 and December 31, 2019, respectively. For the three months ended March 31, 2020, depreciation expense totaled $48.4 million compared to $52.9 million in the prior year comparative period.
Solothurn, Switzerland Manufacturing Facility
In order to support our drug development pipeline, we are building a large-scale biologics manufacturing facility in Solothurn, Switzerland. We expect this facility to be partially operational by the end of 2020. Upon completion, the facility will include 393,000 square feet related to a large-scale biologics manufacturing facility, 290,000 square feet of warehouse, utilities and support space and 51,000 square feet of administrative space. As of March 31, 2020 and December 31, 2019, we had approximately $1.7 billion and $1.9 billion, respectively, capitalized as construction in progress related to this facility. In the first quarter of 2020 we placed approximately $256.8 million of fixed assets in service related to the facility. As of March 31, 2020, we had contractual commitments of approximately $12.1 million outstanding related to the construction of this facility.