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Income Taxes (Details Textual) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2017
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Tax Credit Carryforward [Line Items]        
Deferred tax assets, other   $ 103.7 $ 38.9  
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent   (4.50%) (1.90%) (11.10%)
Statutory rate   21.00% 21.00% 35.00%
Income tax benefit (expense)   $ 1,158.0 $ 1,425.6 $ 2,458.7
Income Taxes Paid   87.0    
Deferred tax liabilities, temporary differences, purchase accounting, foreign subsidiaries   1,500.0    
GILTI   (1,381.6) (544.6)  
Net impairment on certain tax assets $ 48.8     48.8
Decrease in Unrecognized Tax Benefits is Reasonably Possible   75.0    
Income Taxes (Textual)        
Total deferred charges and prepaid taxes   243.8 239.2  
Unrecognized tax benefit 64.3 122.7 109.1 64.3
Net interest expense   4.7 2.2 4.8
Unrecognized Tax Benefits, Interest on Income Taxes Accrued   20.0 $ 13.8  
2017 Tax Act        
Tax Credit Carryforward [Line Items]        
Statutory rate     21.00%  
Income tax benefit (expense)       1,200.0
Transition toll tax liabilities 989.6 697.0   989.6
Income tax expense (benefit) 184.0   $ 12.7  
Reduction in deferred tax liability, undistributed foreign earnings     34.6  
GILTI     135.8  
Other tax expense (benefit)     $ 11.0  
General Business | Domestic Country        
Tax Credit Carryforward [Line Items]        
Operating Loss Carryforwards   0.7    
Tax Credit Carryforward, Amount   1.3    
General Business | State and Local Jurisdiction        
Tax Credit Carryforward [Line Items]        
Deferred Tax Assets, Operating Loss Carryforwards, State and Local   4.6    
General Business | Foreign Tax Authority        
Tax Credit Carryforward [Line Items]        
Operating Loss Carryforwards   1,773.8    
Research | State and Local Jurisdiction        
Tax Credit Carryforward [Line Items]        
Tax Credit Carryforward, Amount   133.8    
Prepaid taxes        
Tax Credit Carryforward [Line Items]        
Net impairment on certain tax assets $ 142.6     $ 142.6
Earnings in the form of cash and cash equivalents | 2017 Tax Act        
Tax Credit Carryforward [Line Items]        
Transition Toll Tax repatriation tax rate 15.50%     15.50%
Other Foreign Earnings | 2017 Tax Act        
Tax Credit Carryforward [Line Items]        
Transition Toll Tax repatriation tax rate 8.00%     8.00%
ZINBRYTA        
Tax Credit Carryforward [Line Items]        
Unrecorded tax benefit       $ 93.8
Minimum        
Tax Credit Carryforward [Line Items]        
Residual U.S. tax liability on reversal of deferred tax liabilities on foreign subsidiaries purchase accounting   300.0    
Maximum        
Tax Credit Carryforward [Line Items]        
Residual U.S. tax liability on reversal of deferred tax liabilities on foreign subsidiaries purchase accounting   400.0    
Denmark Manufacturing Operations        
Tax Credit Carryforward [Line Items]        
Tax expense on disposal group   68.9    
Intellectual Property        
Tax Credit Carryforward [Line Items]        
Deferred Tax Liabilities, Other   603.3    
Deferred tax assets, other   $ 754.1