Income Taxes (Details 2)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Reconciliation between the U.S. federal statutory tax rate and effective tax rate
Statutory rate	21.00%	21.00%	35.00%
State taxes	0.80%	0.60%	0.80%
Taxes on foreign earnings	(4.50%)	(1.90%)	(11.10%)
Credits and net operating loss utilization	(1.10%)	(0.90%)	(0.80%)
Purchased intangible assets	0.40%	1.20%	1.40%
Effective Income Tax Rate Reconciliation, Disposition of Asset, Percent	1.00%	0.00%	0.00%
Effective Income Tax Rate Reconciliation, Intellectual Property Rights Reorganization	(2.10%)	0.00%	0.00%
Manufacturing deduction	0.00%	0.00%	(1.90%)
2017 Tax Act	0.00%	2.10%	22.90%
Effective Income Tax Rate Reconciliation, Change in Foreign Tax Rate, Percent	(0.80%)	0.00%	0.00%
GILTI	1.50%	1.60%	0.00%
Impairment of ZINBRYTA related tax assets	0.00%	0.00%	0.90%
Permanent items	0.20%	0.30%	0.70%
Other	(0.10%)	0.20%	0.00%
Effective tax rate	16.30%	24.20%	47.90%