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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Other Income (Expense), Net          
Interest income $ 30.5 $ 26.0 $ 90.8 $ 81.4  
Interest expense (45.8) (49.0) (141.4) (151.2)  
Gain (loss) on investments, net (4.1) 141.1 198.9 132.0  
Foreign exchange gains (losses), net (4.2) 0.2 (4.7) (13.8)  
Other, net (3.7) (3.2) (11.0) (8.8)  
Total other income (expense), net (27.3) 115.1 132.6 39.6  
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract]          
Net gains (losses) recognized during the period on equity securities (4.6) 141.2 197.3 139.7  
Less: Net gains (losses) recognized during the period on equity securities sold during the period 4.4 0.0 46.8 (0.5)  
Unrealized gains (losses) recognized during the period on equity securities held as of September 30, 2019 (9.0) $ 141.2 150.5 $ 140.2  
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances 1,085.8   1,085.8   $ 1,051.3
Collaboration expenses 259.5   259.5   320.9
Royalties and licensing fees 222.3   222.3   224.7
Collaboration expenses 188.7   188.7   261.6
Current portion of contingent consideration obligations 147.5   147.5   444.8
Construction in progress 49.5   49.5   125.2
Other 677.4   677.4   609.3
Total accrued expenses and other 2,429.1   2,429.1   2,861.2
Component of accrued expenses and other          
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances $ 884.2   $ 884.2   $ 874.7