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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Other Income (Expense), Net          
Interest income $ 26.0 $ 20.6 $ 81.4 $ 54.2  
Interest expense (49.0) (61.8) (151.2) (188.8)  
Gain (loss) on investments, net 141.1 (4.0) 132.0 (15.0)  
Foreign exchange gains (losses), net 0.2 6.7 (13.8) 8.4  
Other, net (3.2) (5.5) (8.8) (9.4)  
Total other income (expense), net 115.1 $ (44.0) 39.6 $ (150.6)  
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances 935.8   935.8   $ 761.6
Current portion of contingent consideration obligations 381.5   381.5   844.6
Employee compensation and benefits 274.1   274.1   297.7
Royalties and licensing fees 226.3   226.3   206.7
Construction in progress 196.6   196.6   159.7
Collaboration expenses 101.5   101.5   183.7
Other 640.0   640.0   636.9
Total accrued expenses and other 2,578.5   2,578.5   2,901.3
Component of accrued expenses and other          
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances $ 758.5   $ 758.5   $ 572.0