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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances $ 865.6   $ 865.6   $ 761.6
Current portion of contingent consideration obligations and milestones 529.4   529.4   844.6
Royalties and licensing fees 218.2   218.2   206.7
Employee compensation and benefits 209.8   209.8   297.7
Construction Payable 179.3   179.3   159.7
Collaboration expenses accrual 156.1   156.1   183.7
Other 638.1   638.1   636.9
Total accrued expenses and other 2,633.7   2,633.7   2,901.3
Other Income (Expense), Net          
Interest income 28.7 $ 16.9 55.4 $ 33.6  
Interest expense (51.7) (63.6) (102.2) (127.0)  
Gain (Loss) on investments, net 5.3 (13.4) (9.1) (11.0)  
Foreign exchange gains (losses), net (13.0) (2.3) (14.0) 1.7  
Other, net (3.8) (6.2) (5.6) (3.9)  
Other income (expense), net (34.5) $ (68.6) (75.5) $ (106.6)  
Component of accrued expenses and other          
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances $ 702.8   $ 702.8   $ 572.0