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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Accrued Expenses and Other      
Revenue-related reserves for discounts and allowances $ 859.3   $ 761.6
Current portion of contingent consideration obligations and milestones 524.3   844.6
Royalties and licensing fees 194.6   206.7
Employee compensation and benefits 186.7   297.7
Construction Payable 178.2   159.7
Collaboration expenses accrual 176.4   183.7
Other 653.4   636.9
Total accrued expenses and other 2,571.1   2,901.3
Other Income (Expense), Net      
Interest income 26.7 $ 16.7  
Interest expense (50.5) (63.4)  
Gain (loss) on sales of investments, net (14.4) 2.4  
Foreign exchange gains (losses), net (1.0) 4.0  
Other, net (1.8) 2.3  
Other income (expense), net (41.0) $ (38.0)  
Component of accrued expenses and other      
Accrued Expenses and Other      
Revenue-related reserves for discounts and allowances $ 657.5   $ 572.0