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Indebtedness (Details)
SFr in Millions, $ in Millions
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2006
CHF (SFr)
Current portion:      
Financing arrangement for the purchase of the RTP facility $ 0.0 $ 1.7  
Current portion of notes payable and other financing arrangements 3.2 4.7  
Non-current portion:      
Non-current notes payable 6,003.2    
Financing arrangement for the purchase of the RTP facility 0.0 16.4  
Non-current portion of notes payable and other financing arrangements 5,935.0 6,512.7  
Note payable to Fumedica      
Current portion:      
Notes payable to Fumedica 3.2 3.0  
Non-current portion:      
Non-current notes payable 0.0 3.0 SFr 61.4
6.875% Senior Notes due 2018      
Non-current portion:      
Non-current notes payable 0.0 558.5  
2.90% Senior Notes due 2020      
Non-current portion:      
Non-current notes payable 1,482.4 1,485.3  
3.625% Senior Notes due 2022      
Non-current portion:      
Non-current notes payable 994.3 993.2  
4.05% Senior Notes due 2025      
Non-current portion:      
Non-current notes payable 1,736.3 1,734.8  
5.20% Senior Notes due 2045      
Non-current portion:      
Non-current notes payable $ 1,722.0 $ 1,721.5