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Property, Plant and Equipment (Details Textual)
SFr in Millions, $ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2017
USD ($)
Mar. 31, 2016
USD ($)
Mar. 31, 2016
CHF (SFr)
Sep. 30, 2015
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Property, Plant and Equipment              
Depreciation expense         $ 266.3 $ 309.3 $ 217.9
Interest cost capitalization related to construction in progress         30.7 12.9 $ 10.4
Construction in progress $ 1,276.0       1,276.0 658.6  
Solothurn              
Property, Plant and Equipment              
Construction in progress 1,200.0       $ 1,200.0 $ 481.5  
Eisai              
Property, Plant and Equipment              
Facility purchase $ 17.2     $ 104.8      
Term of original lease       10 years      
Term of amended lease       3 years      
Capital lease obligation       $ 20.3      
Building | Eisai              
Property, Plant and Equipment              
Facility purchase       58.6      
Machinery and Equipment | Eisai              
Property, Plant and Equipment              
Facility purchase       25.9      
Land | Solothurn              
Property, Plant and Equipment              
Facility purchase   $ 62.5 SFr 64.4        
Land | Eisai              
Property, Plant and Equipment              
Facility purchase       $ 20.3