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Segment Information (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Revenue by product                      
Product, net $ 2,712.4 $ 2,622.5 $ 2,639.7 $ 2,380.1 $ 2,502.9 $ 2,539.6 $ 2,466.0 $ 2,309.4 $ 10,354.7 $ 9,817.9 $ 9,188.5
U.S                      
Revenue by product                      
Product, net                 7,017.1 7,050.4 6,545.8
Rest of world                      
Revenue by product                      
Product, net                 3,337.6 2,767.5 2,642.7
TECFIDERA                      
Revenue by product                      
Product, net                 4,214.0 3,968.1 3,638.4
TECFIDERA | U.S                      
Revenue by product                      
Product, net                 3,294.0 3,169.4 2,908.2
TECFIDERA | Rest of world                      
Revenue by product                      
Product, net                 920.0 798.7 730.2
AVONEX                      
Revenue by product                      
Product, net                 2,151.5 2,313.5 2,630.2
AVONEX | U.S                      
Revenue by product                      
Product, net                 1,593.6 1,675.3 1,790.2
AVONEX | Rest of world                      
Revenue by product                      
Product, net                 557.9 638.2 840.0
PLEGRIDY                      
Revenue by product                      
Product, net                 494.3 481.7 338.5
PLEGRIDY | U.S                      
Revenue by product                      
Product, net                 295.5 305.0 227.1
PLEGRIDY | Rest of world                      
Revenue by product                      
Product, net                 198.8 176.7 111.4
TYSABRI                      
Revenue by product                      
Product, net                 1,973.1 1,963.8 1,886.1
TYSABRI | U.S                      
Revenue by product                      
Product, net                 1,113.8 1,182.9 1,103.1
TYSABRI | Rest of world                      
Revenue by product                      
Product, net                 859.3 780.9 783.0
FAMPYRA                      
Revenue by product                      
Product, net                 91.6 84.9 89.7
FAMPYRA | U.S                      
Revenue by product                      
Product, net                 0.0 0.0 0.0
FAMPYRA | Rest of world                      
Revenue by product                      
Product, net                 91.6 84.9 89.7
ZINBRYTA                      
Revenue by product                      
Product, net                 52.7 7.8 0.0
ZINBRYTA | U.S                      
Revenue by product                      
Product, net                 0.0 0.0 0.0
ZINBRYTA | Rest of world                      
Revenue by product                      
Product, net                 52.7 7.8 0.0
SPINRAZA                      
Revenue by product                      
Product, net                 883.7 4.6 0.0
SPINRAZA | U.S                      
Revenue by product                      
Product, net                 657.0 4.6 0.0
SPINRAZA | Rest of world                      
Revenue by product                      
Product, net                 226.7 0.0 0.0
ELOCTATE                      
Revenue by product                      
Product, net                 48.4 513.2 319.7
ELOCTATE | U.S                      
Revenue by product                      
Product, net                 42.2 445.2 308.3
ELOCTATE | Rest of world                      
Revenue by product                      
Product, net                 6.2 68.0 11.4
ALPROLIX                      
Revenue by product                      
Product, net                 26.0 333.7 234.5
ALPROLIX | U.S                      
Revenue by product                      
Product, net                 21.0 268.0 208.9
ALPROLIX | Rest of world                      
Revenue by product                      
Product, net                 5.0 65.7 25.6
FUMADERM                      
Revenue by product                      
Product, net                 39.6 45.9 51.4
FUMADERM | U.S                      
Revenue by product                      
Product, net                 0.0 0.0 0.0
FUMADERM | Rest of world                      
Revenue by product                      
Product, net                 39.6 45.9 51.4
BENEPALI                      
Revenue by product                      
Product, net                 370.8 100.6 0.0
BENEPALI | U.S                      
Revenue by product                      
Product, net                 0.0 0.0 0.0
BENEPALI | Rest of world                      
Revenue by product                      
Product, net                 370.8 100.6 0.0
FLIXABI                      
Revenue by product                      
Product, net                 9.0 0.1 0.0
FLIXABI | U.S                      
Revenue by product                      
Product, net                 0.0 0.0 0.0
FLIXABI | Rest of world                      
Revenue by product                      
Product, net                 $ 9.0 $ 0.1 $ 0.0