Acquisitions (Details Textual) $ in Millions	6 Months Ended
Jun. 30, 2017 USD ($)
Remedy Pharmaceutical [Member]
Business Acquisition [Line Items]
Acquired in-process research and development	$ 120.0

The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 13
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585

Name:	us-gaap_PaymentsToAcquireBusinessesGross
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration