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Collaborative and Other Relationships Collaborative and Other Relationships - Collaborations (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Mar. 31, 2016
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Research and development $ 423.4     $ 437.3
Other 90.0     87.9
Product, net 2,380.1     $ 2,309.4
Bristol-Myers Squibb        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Research and development 300.0      
Additional milestone payments 410.0      
iPerian        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Additional milestone payments $ 550.0      
AbbVie        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Biogen share of co-promotion profits or losses 50.00%      
AbbVie | U.S.        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Other $ 5.9      
Ionis Pharmaceuticals [Member]        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
License Fee     $ 75.0  
Ionis Pharmaceuticals [Member] | SPINRAZA        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Additional milestone payments 90.0      
Ionis Pharmaceuticals [Member] | SPINRAZA | U.S.        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Product, net 46.4      
Ionis Pharmaceuticals [Member] | SPINRAZA | Rest of world        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Product, net $ 1.0      
Acquired and in-licensed rights and patents | SPINRAZA        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Increase in acquired and in-licensed rights and patents   $ 60.0    
Minimum | Ionis Pharmaceuticals [Member] | SPINRAZA        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Royalty payments per the collaboration 11.00%      
Maximum | Ionis Pharmaceuticals [Member] | SPINRAZA        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Royalty payments per the collaboration 15.00%      
FY 2017 | iPerian        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Additional milestone payments $ 60.0