Indebtedness (Details) SFr in Millions, $ in Millions	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2006 CHF (SFr)
Current portion:
Financing arrangement for the purchase of the RTP facility	$ 1.7	$ 1.7
Current portion of notes payable and other financing arrangements	4.7	4.8
Non-current portion:
Non-current notes payable	6,556.2
Financing arrangement for the purchase of the RTP facility	16.4	18.1
Non-current portion of notes payable and other financing arrangements	6,512.7	6,521.5
Note payable to Fumedica
Current portion:
Notes payable to Fumedica	3.0	3.1
Non-current portion:
Non-current notes payable	3.0	5.9	SFr 61.4
6.875% Senior Notes due 2018
Non-current portion:
Non-current notes payable	558.5	565.3
2.90% Senior Notes due 2020
Non-current portion:
Non-current notes payable	1,485.3	1,485.5
3.625% Senior Notes due 2022
Non-current portion:
Non-current notes payable	993.2	992.2
4.05% Senior Notes due 2025
Non-current portion:
Non-current notes payable	1,734.8	1,733.4
5.20% Senior Notes due 2045
Non-current portion:
Non-current notes payable	$ 1,721.5	$ 1,721.1