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Property, Plant and Equipment (Details Textual) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2016
Sep. 30, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Property, Plant and Equipment          
Depreciation expense     $ 309.3 $ 217.9 $ 198.4
Interest cost capitalization related to construction in progress     12.9 10.4 $ 6.4
Construction in progress     658.6 441.2  
Solothurn          
Property, Plant and Equipment          
Construction in progress     481.5 99.0  
Eisai          
Property, Plant and Equipment          
Facility Purchase   $ 104.8      
Term of original lease   10 years      
Term of amended lease   3 years      
Capital lease obligation   $ 20.3 $ 18.1 $ 19.8  
Building | Eisai          
Property, Plant and Equipment          
Facility Purchase   58.6      
Machinery and Equipment | Eisai          
Property, Plant and Equipment          
Facility Purchase   25.9      
Land | Eisai          
Property, Plant and Equipment          
Facility Purchase   $ 20.3      
Swiss francs | Land | Solothurn          
Property, Plant and Equipment          
Facility Purchase $ 64.4        
United States of America, Dollars | Land | Solothurn          
Property, Plant and Equipment          
Facility Purchase $ 62.5