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Intangible Assets and Goodwill (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Feb. 12, 2015
Finite-Lived Intangible Assets [Line Items]          
Increase to goodwill   $ 1,026.9 $ 908.1    
Goodwill $ 3,669.3 3,669.3 2,663.8 $ 1,760.2  
Intangible assets          
Total intangible assets, gross 7,742.3 7,742.3 7,646.3    
Accumulated Amortization (3,934.0) (3,934.0) (3,561.2)    
Intangible assets, net 3,808.3 3,808.3 4,085.1    
Intangible Assets and Goodwill (Additional Textual)          
Expected future amortization expense, 2017 334.8 334.8      
Expected future amortization expense, 2018 312.7 312.7      
Expected future amortization expense, 2019 295.2 295.2      
Expected future amortization expense, 2020 259.7 259.7      
Expected future amortization expense, 2021 242.8 242.8      
Amortization of acquired intangible assets   (385.6) (382.6) (489.8)  
Deferred tax liabilities 376.6 376.6 440.1    
Out-licensed patents          
Intangible assets          
Cost 543.3 543.3 543.3    
Accumulated Amortization (523.6) (523.6) (506.0)    
Net 19.7 $ 19.7 37.3    
Intangible Assets and Goodwill (Additional Textual)          
Impairment of out-licensed patent       34.7  
Out-licensed patents | Minimum          
Intangible assets          
Estimated life, (In Years)   13 years      
Out-licensed patents | Maximum          
Intangible assets          
Estimated life, (In Years)   23 years      
Developed technology          
Intangible assets          
Cost 3,005.3 $ 3,005.3 3,005.3    
Accumulated Amortization (2,634.3) (2,634.3) (2,552.9)    
Net 371.0 $ 371.0 452.4    
Developed technology | Minimum          
Intangible assets          
Estimated life, (In Years)   15 years      
Developed technology | Maximum          
Intangible assets          
Estimated life, (In Years)   23 years      
Acquired and in-licensed rights and patents          
Intangible assets          
Cost 3,481.7 $ 3,481.7 3,303.2    
Accumulated Amortization (776.1) (776.1) (502.3)    
Net 2,705.6 $ 2,705.6 2,800.9    
Acquired and in-licensed rights and patents | Minimum          
Intangible assets          
Estimated life, (In Years)   6 years      
Acquired and in-licensed rights and patents | Maximum          
Intangible assets          
Estimated life, (In Years)   18 years      
In-process research and development          
Intangible assets          
Indefinite lived intangible assets useful life   Indefinite      
Cost and net 648.0 $ 648.0 730.5    
Accumulated Amortization 0.0 0.0 0.0    
Intangible Assets and Goodwill (Additional Textual)          
Impairment of out-licensed patent   $ 12.2   $ 16.2  
Trademarks and trade names          
Intangible assets          
Indefinite lived intangible assets useful life   Indefinite      
Cost and net 64.0 $ 64.0 64.0    
Accumulated Amortization 0.0 0.0 0.0    
AVONEX | Developed technology          
Intangible assets          
Net 363.3 363.3      
TYSABRI | Acquired and in-licensed rights and patents          
Intangible assets          
Net 2,493.2 2,493.2      
SPINRAZA | Acquired and in-licensed rights and patents          
Intangible Assets and Goodwill (Additional Textual)          
Net change in acquired and in-licensed rights and patents   60.0      
Biosimilars | Acquired and in-licensed rights and patents          
Intangible Assets and Goodwill (Additional Textual)          
Net change in acquired and in-licensed rights and patents   50.0      
ZINBRYTA | Acquired and in-licensed rights and patents          
Intangible Assets and Goodwill (Additional Textual)          
Net change in acquired and in-licensed rights and patents   32.0      
ALPROLIX | Acquired and in-licensed rights and patents          
Intangible Assets and Goodwill (Additional Textual)          
Net change in acquired and in-licensed rights and patents   26.5      
Milestone payment made during period   20.0      
Deferred tax liabilities 6.5 6.5      
Convergence Pharmaceuticals          
Finite-Lived Intangible Assets [Line Items]          
Goodwill         $ 128.3
Intangible Assets and Goodwill (Additional Textual)          
In-process research and development         $ 424.6
Milestone payment made during period $ 50.0        
Fumapharm AG | TECFIDERA          
Finite-Lived Intangible Assets [Line Items]          
Increase to goodwill   1,200.0 $ 900.0    
Rodin Therapeutics | In-process research and development          
Intangible Assets and Goodwill (Additional Textual)          
Impairment of out-licensed patent   8.7      
Ataxion | In-process research and development          
Intangible Assets and Goodwill (Additional Textual)          
Impairment of out-licensed patent   $ 3.5