XML 169 R114.htm IDEA: XBRL DOCUMENT v3.6.0.2
Collaborative and Other Relationships (Details Textual)
$ in Millions, ₩ in Billions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Feb. 29, 2012
USD ($)
Dec. 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
Jun. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Sep. 30, 2015
USD ($)
Jun. 30, 2015
USD ($)
Mar. 31, 2015
USD ($)
Jun. 30, 2014
USD ($)
Dec. 31, 2013
USD ($)
Sep. 30, 2013
USD ($)
Dec. 31, 2012
USD ($)
Jun. 30, 2012
USD ($)
Mar. 31, 2012
USD ($)
Jun. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Mar. 31, 2014
USD ($)
Feb. 29, 2012
KRW (₩)
Jan. 31, 2007
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN   $ 2,502.9 $ 2,539.6 $ 2,466.0 $ 2,309.4 $ 2,425.9 $ 2,391.7 $ 2,198.6 $ 2,172.3               $ 9,817.9 $ 9,188.5 $ 8,203.4      
Research and development                                 1,973.3 2,012.8 1,893.4      
Other revenues from external customers   50.9 $ 98.6 79.0 $ 87.9 79.5 49.0 $ 55.6 $ 52.0               316.4 236.1 304.5      
Prepaid research and development   1,335.8       1,107.6                     1,335.8 1,107.6        
Potential future milestone payments commitment, approximately   3,100.0                             3,100.0          
Income (Loss) from Equity Method Investments                                 0.0 (12.5) (15.1)      
Biogen Hemophilia                                            
Collaborative and Other Relationships (Textual)                                            
Stock acquired in acquisition                                           100.00%
Acorda                                            
Collaborative and Other Relationships (Textual)                                            
Expected additional milestone payments for successful achievement of regulatory and commercial sales milestones   375.0                             375.0          
Expected additional milestone payments when certain sales threshold is met   15.0                             15.0          
Foreign sales required to trigger milestone                                 100.0          
Biogen's share of expense reflected within our consolidation statements of income                                 31.5 30.6 29.2      
AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of pre-tax profits in the U.S. for RITUXAN and GAZYVA, including the reimbursement of selling and development expenses                                 21.9          
Total expense incurred by collaboration                                 $ 50.0          
Biogen share of co-promotion profits or losses                                 50.00%          
Swedish Orphan Biovitrum                                            
Collaborative and Other Relationships (Textual)                                            
Consideration per product                                 $ 10.0          
Reimbursement cost achieving period                                 6 years          
Time period for paying remaining balance due                                 90 days          
Ionis Pharmaceuticals, Inc.                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                       $ 75.0 $ 30.0       $ 5.5 20.0 20.0      
Term of collaboration agreement                       6 years                    
Total upfront and milestone payments made to collaborative partner                       $ 100.0                    
Prepaid research and discovery services                       $ 25.0                    
License Fee                                 70.0          
Expected License Fee And Regulatory Milestone Payments   130.0                             130.0          
Additional milestone payments for product candidate using a different modality                                 90.0          
Additional milestone payment   10.0                             10.0          
Eisai                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 50.5 40.4 29.1      
Research and development                   $ 21.6             50.0          
Total expense incurred by collaboration                                 95.1 84.1 57.5      
Total upfront and milestone payments made to collaborative partner                                       $ 100.0    
Additional milestone payment   1,000.0                             1,000.0          
Milestone payment made during period                   $ 35.0                        
AGTC                                            
Collaborative and Other Relationships (Textual)                                            
Research and development             48.1                   26.5 54.5        
Total upfront and milestone payments made to collaborative partner             124.0                              
Prepaid research and discovery services             58.4                              
Additional milestone payment   1,100.0                             1,100.0          
Purchase of common stock             30.0                              
Total licensing and other fees             $ 35.6                              
Research and development services                                   6.5        
Premium on equity investment                                   7.5        
University of Pennsylvania                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                               $ 20.0            
Prepaid research and development       $ 15.0                       $ 15.0            
Future research and development commitment   47.5                             47.5          
Potential future milestone payments commitment, approximately   2,000.0                             2,000.0          
Sangamo BioSciences                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 13.4 13.6 28.9      
Total upfront and milestone payments made to collaborative partner                                       20.0    
Additional milestone payment   $ 300.0                             300.0          
Mitsubishi Tanabe Pharma Corporation                                            
Collaborative and Other Relationships (Textual)                                            
Research and development           $ 60.0                     22.8          
Other research and discovery                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                                 10.3 $ 9.7 $ 40.0      
Samsung Biosimilar Agreement                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                     $ 46.0                      
Collaboration profit (loss) sharing                                 $ 15.1          
Equity Method Investments, Expected Profit Share                                 50.00%          
RITUXAN                                            
Collaborative and Other Relationships (Textual)                                            
Percentage of Co promotion Operating Profits first fifty million   30.00%                             30.00%          
Percentage of share of Co promotion profits exceeding $50 million   39.00%       40.00%                     39.00% 40.00% 40.00%      
Percentage Of Co Promotion Operating Profits Greater Than First Fifty Million Option Two Sub Option One   39.00%                             39.00%          
Percentage Of Co Promotion Operating Profits Greater Than First Fifty Million Option One   40.00%                             40.00%          
GAZYVA                                            
Collaborative and Other Relationships (Textual)                                            
Percentage of Co promotion Operating Profits first fifty million   35.00%                             35.00%          
Co-promotion operating profit threshold for Rituxan in U S and Canada to determine share of co promotion operating profit prior to amendment   $ 50.0                             $ 50.0          
Limit of gross sale of GAZYVA to be achieved in preceding 12 months under option one                                 150.0          
Limit of gross sale of GAZYVA to be achieved in any 12 months under option one                                 150.0          
Sales Trigger Gross Sales Threshold                                 $ 500.0          
Percentage Of Co Promotion Operating Losses                                 35.00%          
Percentage Of Co Promotion Operating Profits Greater Than First Fifty Million Option Two Sub Option One   39.00%                             39.00%          
New Anti-CD20 | Minimum                                            
Collaborative and Other Relationships (Textual)                                            
Future percentage of co-promotion operating profits                                 30.00%          
New Anti-CD20 | Maximum                                            
Collaborative and Other Relationships (Textual)                                            
Future percentage of co-promotion operating profits                                 38.00%          
Ocrelizumab                                            
Collaborative and Other Relationships (Textual)                                            
Reduction in royalty rate                                 50.00%          
Period of collaboration agreement                                 11 years          
Ocrelizumab | Minimum                                            
Collaborative and Other Relationships (Textual)                                            
Future royalties percentage to be received on sale of ocrelizumab                                 13.50%          
Ocrelizumab | Maximum                                            
Collaborative and Other Relationships (Textual)                                            
Future royalties percentage to be received on sale of ocrelizumab                                 24.00%          
ZINBRYTA                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN                                 $ 7.8 $ 0.0 $ 0.0      
Research and development                                   16.0        
ZINBRYTA | AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 24.3 60.8 67.4      
ELOCTATE                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN                                 513.2 319.7 58.4      
ELOCTATE | Swedish Orphan Biovitrum                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                                 144.0          
ALPROLIX | Swedish Orphan Biovitrum                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                                 123.0          
SPINRAZA                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN                                 4.6 0.0 0.0      
SPINRAZA | Ionis Pharmaceuticals, Inc.                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 257.8 74.9 27.7      
Research and development                             $ 29.0   35.3 42.8 57.3      
Estimated additional payments upon achievement of development and commercial milestones.   $ 90.0                             90.0          
SOD1 | Ionis Pharmaceuticals, Inc.                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                                   10.0        
DMPK | Ionis Pharmaceuticals, Inc.                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 3.1 9.0 10.9      
Research and development                           $ 12.0                
Additional milestone payment           $ 4.2               $ 59.0       4.2        
Lead programs | AGTC                                            
Collaborative and Other Relationships (Textual)                                            
Research and development                                   5.0        
Additional milestone payment   472.5                             472.5          
Discovery programs | AGTC                                            
Collaborative and Other Relationships (Textual)                                            
Additional milestone payment   592.5                             592.5          
Samsung Biosimilar Agreement                                            
Collaborative and Other Relationships (Textual)                                            
Other revenues from external customers                                 20.2 62.9 58.5      
Additional milestone payment   $ 25.0                             $ 25.0          
Investments By Third Party In Joint Venture As Per Agreement. $ 250.0                                       ₩ 280.5  
Joint Venture Owner Ship Percentage By Third Party. 85.00%                                          
Equity Method Investments $ 45.0                                       ₩ 49.5  
Percentage of equity interest to the portion of total capital stock 15.00% 6.50%                             6.50%       15.00%  
Equity Method Investment Ownership Percentage Maximum 49.90%                                          
Revenue | Swedish Orphan Biovitrum                                            
Collaborative arrangements and non-collaborative arrangement transactions                                            
Biogen effective royalty rate                                 0.14          
Cost of sales | Swedish Orphan Biovitrum                                            
Collaborative arrangements and non-collaborative arrangement transactions                                            
Biogen effective royalty rate                                 0.11          
Research and development | AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Total expense incurred by collaboration                                 $ 48.6 113.8 117.8      
Research and development | Eisai                                            
Collaborative and Other Relationships (Textual)                                            
Amount recorded to reflect fair value of options granted                                       $ 17.7    
Selling, general and administrative | ZINBRYTA | AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of expense reflected within our consolidation statements of income                                 22.0          
U.S                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN                                 7,050.4 6,545.8 5,566.7      
Other revenues from external customers                                 224.7 142.0 212.6      
U.S | Roche Group - Genentech                                            
Collaborative and Other Relationships (Textual)                                            
Biogen's share of pre-tax profits in the U.S. for RITUXAN and GAZYVA, including the reimbursement of selling and development expenses                                 1,249.5 1,269.8 1,117.1      
U.S | AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Other revenues from external customers                                 21.9          
Outside the U.S | RITUXAN | Roche Group - Genentech                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN                                 $ 65.0 69.4 78.3      
Outside the U.S | Ocrelizumab                                            
Collaborative and Other Relationships (Textual)                                            
Future royalties percentage to be received on sale of ocrelizumab                                 3.00%          
Europe                                            
Collaborative and Other Relationships (Textual)                                            
Revenue on sales in the rest of world for RITUXAN [1]                                 $ 1,533.5 1,497.6 1,383.9      
Other revenues from external customers [1]                                 70.0 $ 29.6 $ 31.6      
Europe | AbbVie                                            
Collaborative and Other Relationships (Textual)                                            
Collaboration profit (loss) sharing                                 4.9          
Acquired and in-licensed rights and patents | ZINBRYTA                                            
Collaborative and Other Relationships (Textual)                                            
Net change in acquired and in-licensed rights and patents                                 32.0          
Acquired and in-licensed rights and patents | ALPROLIX                                            
Collaborative and Other Relationships (Textual)                                            
Net change in acquired and in-licensed rights and patents                                 26.5          
Milestone payment made during period                                 20.0          
Acquired and in-licensed rights and patents | SPINRAZA                                            
Collaborative and Other Relationships (Textual)                                            
Net change in acquired and in-licensed rights and patents                                 60.0          
Acquired and in-licensed rights and patents | Biosimilars                                            
Collaborative and Other Relationships (Textual)                                            
Net change in acquired and in-licensed rights and patents                                 $ 50.0          
[1] Represents amounts related to Europe less those attributable to Germany.