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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Millions
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net income $ 3,047.8 $ 2,764.5
Adjustments to reconcile net income to net cash flows from operating activities:    
Depreciation and amortization 505.3 444.1
Share-based compensation 117.8 131.5
Deferred income taxes (56.8) (185.8)
Other 33.4 31.6
Changes in operating assets and liabilities, net:    
Accounts receivable (238.1) (63.6)
Inventory (155.1) (150.4)
Accrued expenses and other current liabilities (223.2) (174.5)
Changes in other tax assets and liabilities, net (147.4) (1.2)
Other changes in operating assets and liabilities, net 62.1 (120.5)
Net cash flows provided by operating activities 2,945.8 2,675.7
Cash flows from investing activities:    
Proceeds from sales and maturities of marketable securities 5,185.8 3,363.4
Purchases of marketable securities (5,631.7) (4,870.1)
Contingent consideration related to Fumapharm AG acquisition 900.0 550.0
Purchases of property, plant and equipment (434.0) (456.9)
Acquisitions of intangible assets (110.4) (6.3)
Acquisitions of business, net of cash acquired 0.0 (198.8)
Other (12.8) (27.4)
Net cash flows used in investing activities (1,903.1) (2,746.1)
Cash flows from financing activities:    
Purchase of treasury stock (348.9) (2,998.2)
Proceeds from issuance of stock for share-based compensation arrangements (35.2) (45.5)
Proceeds from borrowings 0.0 5,930.9
Repayment of borrowings (2.7) (2.1)
Excess tax benefit from share-based awards 11.9 70.8
Other 37.9 (62.1)
Net cash flows (used in) provided by financing activities (266.6) 2,984.8
Net increase in cash and cash equivalents 776.1 2,914.4
Effect of exchange rate changes on cash and cash equivalents 0.7 (30.3)
Cash and cash equivalents, beginning of the period 1,308.0 1,204.9
Cash and cash equivalents, end of the period $ 2,084.8 $ 4,089.0