Financial Instruments

The following table summarizes our financial assets with maturities of less than 90 days from the date of purchase included in cash and cash equivalents on the accompanying condensed consolidated balance sheet:



(In millions)	As of September 30, 2016		As of December 31, 2015
Commercial paper	$	84.2	$	21.9
Overnight reverse repurchase agreements	42.1		134.7
Money market funds	1,600.1		673.8
Short-term debt securities	10.0		79.1
Total	$	1,736.4	$	909.5

The carrying values of our commercial paper, including accrued interest, overnight reverse repurchase agreements, money market funds and our short-term debt securities approximate fair value due to their short-term maturities. Our overnight reverse repurchase agreements are collateralized with agency-guaranteed mortgage-backed securities and represent approximately 0.2% and 0.7% of total assets as of September 30, 2016 and December 31, 2015, respectively.

The following tables summarize our marketable debt and equity securities, classified as available-for-sale:



As of September 30, 2016 (In millions)	Fair Value		Gross Unrealized Gains		Gross Unrealized Losses			Amortized Cost
Corporate debt securities
Current	$	1,293.2	$	0.2	$	(0.3	)	$	1,293.3
Non-current	1,338.9		4.5		(0.7		)	1,335.1
Government securities
Current	938.0		0.6		(0.1		)	937.5
Non-current	1,100.2		1.6		(0.5		)	1,099.1
Mortgage and other asset backed securities
Current	—		—		—			—
Non-current	657.8		1.3		(0.8		)	657.3
Total marketable debt securities	$	5,328.1	$	8.2	$	(2.4	)	$	5,322.3
Marketable equity securities, non-current	$	29.0	$	3.8	$	(8.3	)	$	33.5



As of December 31, 2015 (In millions)	Fair Value		Gross Unrealized Gains		Gross Unrealized Losses			Amortized Cost
Corporate debt securities
Current	$	394.3	$	—	$	(0.5	)	$	394.8
Non-current	1,116.6		0.1		(4.1		)	1,120.6
Government securities
Current	1,723.4		0.1		(1.1		)	1,724.4
Non-current	1,152.5		—		(3.1		)	1,155.6
Mortgage and other asset backed securities
Current	2.8		—		—			2.8
Non-current	491.3		0.1		(1.8		)	493.0
Total marketable debt securities	$	4,880.9	$	0.3	$	(10.6	)	$	4,891.2
Marketable equity securities, non-current	$	37.5	$	9.2	$	—		$	28.3

Summary of Contractual Maturities: Available-for-Sale Securities

The estimated fair value and amortized cost of our marketable debt securities available-for-sale by contractual maturity are summarized as follows:



	As of September 30, 2016				As of December 31, 2015
(In millions)	Estimated Fair Value		Amortized Cost		Estimated Fair Value		Amortized Cost
Due in one year or less	$	2,231.2	$	2,230.8	$	2,120.5	$	2,122.0
Due after one year through five years	2,815.5		2,810.2		2,575.9		2,583.9
Due after five years	281.4		281.3		184.5		185.3
Total available-for-sale securities	$	5,328.1	$	5,322.3	$	4,880.9	$	4,891.2

The average maturity of our marketable debt securities available-for-sale as of September 30, 2016 and December 31, 2015 was approximately 14 months and 16 months, respectively.

Proceeds from Marketable Debt Securities

The proceeds from maturities and sales of marketable debt securities and resulting realized gains and losses are summarized as follows:



	For the Three Months Ended September 30,						For the Nine Months Ended September 30,
(In millions)	2016			2015			2016			2015
Proceeds from maturities and sales	$	2,362.2		$	2,387.9		$	5,185.8		$	3,363.4
Realized gains	$	1.1		$	0.7		$	2.1		$	1.3
Realized losses	$	(1.1	)	$	(2.0	)	$	(2.7	)	$	(2.9	)

Strategic Investments

As of September 30, 2016 and December 31, 2015, our strategic investment portfolio was comprised of investments totaling $94.8 million and $96.0 million, respectively, which are included in investments and other assets in our condensed consolidated balance sheets. Our strategic investment portfolio includes investments in equity securities of certain biotechnology companies and investments in venture capital funds where the underlying investments are in equity securities of biotechnology companies.