Property, Plant and Equipment (Details Textual) SFr in Millions, $ in Millions	3 Months Ended			12 Months Ended
	Dec. 31, 2015 USD ($)	Dec. 31, 2015 CHF (SFr)	Sep. 30, 2015 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)
Property, Plant and Equipment
Depreciation expense				$ 217.9	$ 198.4	$ 187.8
Interest cost capitalization related to construction in progress				10.4	6.4	7.8
Construction in progress	$ 441.2			441.2	$ 168.6
Solothurn
Property, Plant and Equipment
Construction in progress	99.0			99.0
Cambridge Leases
Property, Plant and Equipment
Charges recognized to vacate building						$ 27.2
Eisai
Property, Plant and Equipment
Solothurn, Switzerland land purchase			$ 104.8
Term of original lease			10 years
Term of amended lease			3 years
Capital lease obligation	19.8		$ 20.3	$ 19.8
Land | Solothurn
Property, Plant and Equipment
Solothurn, Switzerland land purchase	$ 62.5	SFr 64.4
Land | Eisai
Property, Plant and Equipment
Solothurn, Switzerland land purchase			$ 20.3