Charge to cost of goods sold that represents the reduction of the carrying amount of inventory, generally attributable to obsolescence or market conditions.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 330
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=28360613&loc=d3e4542-108314

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.2)
-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688

Name:	us-gaap_InventoryWriteDown
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

Inventory (Details Textual) - USD ($) $ in Millions	12 Months Ended
Inventory (Details Textual) - USD ($) $ in Millions	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Inventory [Line Items]
Write-downs on excess, obsolete, unmarketable or other inventory	$ 41.9	$ 50.6	$ 47.3
ZINBRYTA
Inventory [Line Items]
Pre-approval inventory	24.7	$ 6.3
BENEPALI
Inventory [Line Items]
Pre-approval inventory	18.4
FLIXABI
Inventory [Line Items]
Pre-approval inventory	$ 24.2