Intangible Assets and Goodwill (Tables)

9 Months Ended

Sep. 30, 2015

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible assets, net of accumulated amortization, impairment charges and adjustments, are summarized as follows:



		As of September 30, 2015							As of December 31, 2014
(In millions)	Estimated Life	Cost		Accumulated Amortization			Net		Cost		Accumulated Amortization			Net
Out-licensed patents	13-23 years	$	543.3	$	(499.9	)	$	43.4	$	543.3	$	(481.7	)	$	61.6
Developed technology	15-23 years	3,005.3		(2,523.8		)	481.5		3,005.3		(2,396.8		)	608.5
In-process research and development	Indefinite until commercialization	735.6		—			735.6		314.1		—			314.1
Trademarks and tradenames	Indefinite	64.0		—			64.0		64.0		—			64.0
Acquired and in-licensed rights and patents	3-17 years	3,297.6		(440.9		)	2,856.7		3,280.4		(300.1		)	2,980.3
Total intangible assets		$	7,645.8	$	(3,464.6	)	$	4,181.2	$	7,207.1	$	(3,178.6	)	$	4,028.5

Estimated future amortization for acquired intangible assets

Based upon this analysis, there was not a significant change in our expected rate of amortization for acquired intangible assets and the estimated future amortization is expected to be as follows:



(In millions)	As of September 30, 2015
2015 (remaining three months)	$	94.3
2016	348.8
2017	318.6
2018	291.0
2019	275.1
2020	269.1
Total	$	1,596.9

Summary of roll forward of the changes in goodwill

The following table provides a roll forward of the changes in our goodwill balance:



(In millions)
Balance, as of December 31, 2014	$	1,760.2
Increase to goodwill	649.4
Other	(0.7		)
Balance, as of September 30, 2015	$	2,408.9