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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Cash flows from operating activities:    
Net income $ 1,744,999 $ 1,202,860
Adjustments to reconcile net income to net cash flows from operating activities:    
Depreciation and amortization 292,523 355,102
Share-based compensation 93,677 83,856
Deferred income taxes (90,647) (146,506)
Other (5,808) (64,213)
Changes in operating assets and liabilities, net:    
Accounts receivable (38,907) (188,961)
Inventory (81,294) (72,689)
Accrued expenses and other current liabilities (169,929) (30,299)
Current taxes payable 102,017 31,113
Other changes in operating assets and liabilities, net (66,374) (75,044)
Net cash flows provided by operating activities 1,780,257 1,095,219
Cash flows from investing activities:    
Proceeds from sales and maturities of marketable securities 975,517 1,317,525
Purchases of marketable securities (2,045,046) (1,787,606)
Acquisitions of business, net of cash acquired (198,798) 0
Purchases of property, plant and equipment (227,688) (118,308)
Contingent consideration related to Fumapharm AG acquisition 250,000 25,000
Other (10,119) (10,745)
Net cash flows used in investing activities (1,756,134) (624,134)
Cash flows from financing activities:    
Purchase of treasury stock (42,193) (336,905)
Proceeds from issuance of stock for share-based compensation arrangements 34,727 33,477
Excess tax benefit from stock options 69,690 83,940
Other 14,995 12,003
Net cash flows provided by (used in) financing activities 77,219 (207,485)
Net increase in cash and cash equivalents 101,342 263,600
Effect of exchange rate changes on cash and cash equivalents (24,188) (2,965)
Cash and cash equivalents, beginning of the period 1,204,924 602,562
Cash and cash equivalents, end of the period $ 1,282,078 $ 863,197