Intangible Assets and Goodwill (Tables)

3 Months Ended

Mar. 31, 2015

Goodwill and Intangible Assets Disclosure [Abstract]

Intangible assets

Intangible assets, net of accumulated amortization, impairment charges and adjustments, are summarized as follows:

		As of March 31, 2015							As of December 31, 2014
(In millions)	Estimated Life	Cost		Accumulated Amortization			Net		Cost		Accumulated Amortization			Net
Out-licensed patents	13-23 years	$	543.3	$	(487.8	)	$	55.5	$	543.3	$	(481.7	)	$	61.6
Developed  technology	15-23 years	3,005.3		(2,447.5		)	557.8		3,005.3		(2,396.8		)	608.5
In-process research and development	Indefinite until commercialization	726.1		—			726.1		314.1		—			314.1
Trademarks and  tradenames	Indefinite	64.0		—			64.0		64.0		—			64.0
Acquired and in-licensed rights  and patents	6-17 years	3,288.9		(339.2		)	2,949.7		3,280.4		(300.1		)	2,980.3
Total intangible assets		$	7,627.6	$	(3,274.5	)	$	4,353.1	$	7,207.1	$	(3,178.6	)	$	4,028.5

Estimated future amortization for acquired intangible assets

Based upon this recent analysis, the estimated future amortization for acquired intangible assets is expected to be as follows:

(In millions)	As of March 31, 2015
2015 (remaining nine months)	$	269.0
2016	313.3
2017	286.1
2018	281.6
2019	270.4
2020	263.4
Total	$	1,683.8

Summary of roll forward of the changes in goodwill

The following table provides a roll forward of the changes in our goodwill balance:

(In millions)	As of March 31, 2015
Goodwill, beginning of period	$	1,760.2
Increase to goodwill	92.3
Other	(2.7		)
Goodwill, end of period	$	1,849.9