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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Cash flows from operating activities:      
Net income $ 2,941,565us-gaap_ProfitLoss $ 1,862,341us-gaap_ProfitLoss $ 1,380,033us-gaap_ProfitLoss
Adjustments to reconcile net income to net cash flows from operating activities:      
Depreciation and amortization 688,150us-gaap_DepreciationDepletionAndAmortization 531,740us-gaap_DepreciationDepletionAndAmortization 365,648us-gaap_DepreciationDepletionAndAmortization
Share-based compensation 155,302us-gaap_ShareBasedCompensation 136,293us-gaap_ShareBasedCompensation 118,566us-gaap_ShareBasedCompensation
Deferred income taxes (308,222)us-gaap_DeferredIncomeTaxExpenseBenefit (245,077)us-gaap_DeferredIncomeTaxExpenseBenefit (116,900)us-gaap_DeferredIncomeTaxExpenseBenefit
Other (50,320)us-gaap_OtherNoncashIncomeExpense (27,612)us-gaap_OtherNoncashIncomeExpense 28,822us-gaap_OtherNoncashIncomeExpense
Changes in operating assets and liabilities, net:      
Accounts receivable (512,389)us-gaap_IncreaseDecreaseInAccountsReceivable (126,753)us-gaap_IncreaseDecreaseInAccountsReceivable 3,571us-gaap_IncreaseDecreaseInAccountsReceivable
Inventory (185,917)us-gaap_IncreaseDecreaseInInventories (243,960)us-gaap_IncreaseDecreaseInInventories (140,309)us-gaap_IncreaseDecreaseInInventories
Other assets (94,514)us-gaap_IncreaseDecreaseInOtherOperatingAssets (160,188)us-gaap_IncreaseDecreaseInOtherOperatingAssets (27,347)us-gaap_IncreaseDecreaseInOtherOperatingAssets
Accrued expenses and other current liabilities 244,378us-gaap_IncreaseDecreaseInAccruedLiabilities 284,049us-gaap_IncreaseDecreaseInAccruedLiabilities 273,372us-gaap_IncreaseDecreaseInAccruedLiabilities
Other liabilities and taxes payable 94,779us-gaap_IncreaseDecreaseInOtherOperatingLiabilities 318,512us-gaap_IncreaseDecreaseInOtherOperatingLiabilities 34,112us-gaap_IncreaseDecreaseInOtherOperatingLiabilities
Other (30,697)us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet 15,733us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet (39,671)us-gaap_IncreaseDecreaseInOtherOperatingCapitalNet
Net cash flows provided by operating activities 2,942,115us-gaap_NetCashProvidedByUsedInOperatingActivities 2,345,078us-gaap_NetCashProvidedByUsedInOperatingActivities 1,879,897us-gaap_NetCashProvidedByUsedInOperatingActivities
Cash flows from investing activities:      
Proceeds from sales and maturities of marketable securities 2,718,923us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities 5,190,052us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities 2,749,558us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
Purchases of marketable securities (3,583,150)us-gaap_PaymentsToAcquireAvailableForSaleSecurities (3,278,091)us-gaap_PaymentsToAcquireAvailableForSaleSecurities (3,334,434)us-gaap_PaymentsToAcquireAvailableForSaleSecurities
Acquisition of TYSABRI rights 0us-gaap_PaymentsToAcquireIntangibleAssets (3,262,719)us-gaap_PaymentsToAcquireIntangibleAssets 0us-gaap_PaymentsToAcquireIntangibleAssets
Contingent consideration related to Fumapharm AG acquisition (375,000)us-gaap_PaymentsToAcquireOtherProductiveAssets (15,000)us-gaap_PaymentsToAcquireOtherProductiveAssets 0us-gaap_PaymentsToAcquireOtherProductiveAssets
Acquisitions of businesses 0us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired 0us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired (72,401)us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired
Purchases of property, plant and equipment (287,751)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (246,281)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (254,548)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Other (15,998)us-gaap_PaymentsForProceedsFromOtherInvestingActivities 7,371us-gaap_PaymentsForProceedsFromOtherInvestingActivities (38,517)us-gaap_PaymentsForProceedsFromOtherInvestingActivities
Net cash flows used in investing activities (1,542,976)us-gaap_NetCashProvidedByUsedInInvestingActivities (1,604,668)us-gaap_NetCashProvidedByUsedInInvestingActivities (950,342)us-gaap_NetCashProvidedByUsedInInvestingActivities
Cash flows from financing activities:      
Purchase of treasury stock (886,779)us-gaap_PaymentsForRepurchaseOfCommonStock (400,309)us-gaap_PaymentsForRepurchaseOfCommonStock (984,715)us-gaap_PaymentsForRepurchaseOfCommonStock
Proceeds from issuance of stock for share-based compensation arrangements 54,887us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions 66,770us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions 67,493us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
Excess tax benefit from share-based compensation 96,376us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities 73,467us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities 54,738us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities
Repayments of borrowings (2,674)us-gaap_RepaymentsOfDebt (452,340)us-gaap_RepaymentsOfDebt (2,428)us-gaap_RepaymentsOfDebt
Other (17,683)us-gaap_ProceedsFromPaymentsForOtherFinancingActivities (4,116)us-gaap_ProceedsFromPaymentsForOtherFinancingActivities (12,566)us-gaap_ProceedsFromPaymentsForOtherFinancingActivities
Net cash flows used in financing activities (755,873)us-gaap_NetCashProvidedByUsedInFinancingActivities (716,528)us-gaap_NetCashProvidedByUsedInFinancingActivities (877,478)us-gaap_NetCashProvidedByUsedInFinancingActivities
Net increase (decrease) in cash and cash equivalents 643,266us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 23,882us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease 52,077us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Effect of exchange rate changes on cash and cash equivalents (40,904)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents 7,959us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents 4,102us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents
Cash and cash equivalents, beginning of the year 602,562us-gaap_CashAndCashEquivalentsAtCarryingValue 570,721us-gaap_CashAndCashEquivalentsAtCarryingValue 514,542us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of the year $ 1,204,924us-gaap_CashAndCashEquivalentsAtCarryingValue $ 602,562us-gaap_CashAndCashEquivalentsAtCarryingValue $ 570,721us-gaap_CashAndCashEquivalentsAtCarryingValue