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Investments in Variable Interest Entities (Details Textual) (USD $)
In Millions, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Investment in Variable Interest Entities (Textual)        
Percentage of operations of joint venture investments on financial statements     100.00%  
Percentage of net income (loss) attributable to noncontrolling interests     50.00%  
Investment in biotechnology companies that are determined to be unconsolidated variable interest entities $ 5.5 $ 9.4    
Knopp
       
Investment in Variable Interest Entities (Textual)        
Total upfront and reimbursement payment made to collaborative partner       26.4
Purchase consideration for variable interest entities       60.0
Research and development expense   12.3    
Percentage of funding for R&D cost required in support of the collaboration agreement 100.00%      
Milestone payments made during period 0 0 10.0  
Neurimmune
       
Investment in Variable Interest Entities (Textual)        
Percentage of funding for R&D cost required in support of the collaboration agreement 100.00%      
Remaining potential development milestone payments and royalties on commercial sales under the terms of collaboration agreement 345.0      
Milestone payments made during period $ 0 $ 0 $ 15.0  
Common Class B | Knopp
       
Investment in Variable Interest Entities (Textual)        
Purchase of common shares in variable interest entities       30.00%