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Other Consolidated Financial Statement Detail (Details) (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Other Income (Expense), Net          
Interest income $ 1,500,000 $ 5,900,000 $ 6,700,000 $ 22,600,000  
Interest expense (6,600,000) (8,700,000) (25,500,000) (23,100,000)  
Impairment of investments 0 (3,500,000) (1,700,000) (4,800,000)  
Gain (loss) on sales of investments, net 3,900,000 1,300,000 14,000,000 15,600,000  
Foreign exchange gains (losses), net (3,100,000) 100,000 (11,000,000) 200,000  
Other, net (300,000) 400,000 (12,000,000) 3,100,000  
Total other income (expense), net (4,640,000) (4,548,000) (29,525,000) 13,546,000  
Accrued Expenses and Other          
Employee-related Liabilities 261,500,000   261,500,000   248,500,000
Revenue-related rebates 247,400,000   247,400,000   191,000,000
Deferred revenue 240,700,000   240,700,000   148,000,000
Royalties and licensing fees 117,300,000   117,300,000   45,200,000
Clinical development expenses 57,100,000   57,100,000   51,600,000
Production expenses accrual 43,600,000   43,600,000   45,600,000
Current portion of contingent consideration obligations 29,100,000   29,100,000   22,400,000
Construction in progress accrual 21,900,000   21,900,000   12,300,000
Other 185,800,000   185,800,000   215,300,000
Total accrued expenses and other $ 1,204,437,000   $ 1,204,437,000   $ 979,945,000