Intangible Assets and Goodwill (Details) (USD $)	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012	Dec. 31, 2012
Intangible assets
Total intangible assets, gross	$ 4,032,500,000		$ 4,031,100,000
Accumulated Amortization	(2,451,000,000)		(2,399,600,000)
Intangible assets, net	1,581,511,000		1,631,547,000
Intangible Assets and Goodwill (Additional Textual) [Abstract]
Expected future amortization expense, 2013	277,000,000
Expected future amortization expense, 2014	367,700,000
Expected future amortization expense, 2015	362,800,000
Expected future amortization expense, 2016	365,800,000
Expected futured amortization expense, 2017	355,100,000
FiniteLivedIntangibleAssetsFutureAmortization	1,728,400,000
Intangible Assets and Goodwill (Textual) [Abstract]
Amortization of acquired intangible assets	51,301,000	45,961,000
Accumulated impairment losses related to goodwill	0
VP1 Protein [Member]
Intangible assets
Total intangible assets, gross	27,100,000		25,700,000
Out-licensed patents [Member]
Intangible assets
Cost	578,000,000		578,000,000
Accumulated Amortization	(428,500,000)		(421,000,000)
Net	149,500,000		157,000,000
Out-licensed patents [Member] | Maximum [Member]
Intangible assets
Estimated Life, (In Years)	23 years
Out-licensed patents [Member] | Minimum [Member]
Intangible assets
Estimated Life, (In Years)	13 years
Core developed technology [Member]
Intangible assets
Cost	3,005,300,000		3,005,300,000
Accumulated Amortization	(2,006,900,000)		(1,965,700,000)
Net	998,400,000		1,039,600,000
Core developed technology [Member] | Maximum [Member]
Intangible assets
Estimated Life, (In Years)	23 years
Core developed technology [Member] | Minimum [Member]
Intangible assets
Estimated Life, (In Years)	15 years
Acquired and in-licensed rights and patents [Member]
Intangible assets
Cost	55,100,000		53,700,000
Accumulated Amortization	(15,600,000)		(12,900,000)
Net	39,500,000		40,800,000
Acquired and in-licensed rights and patents [Member] | Maximum [Member]
Intangible assets
Estimated Life, (In Years)	16 years
Acquired and in-licensed rights and patents [Member] | Minimum [Member]
Intangible assets
Estimated Life, (In Years)	6 years
In-process research and development [Member]
Intangible assets
Estimated Life, (In Years)	15 years
Cost and Net	330,100,000		330,100,000
Accumulated Amortization	0		0
Trademarks and trade names [Member]
Intangible assets
Indefinite Lived Intangible Assets Useful Life	Indefinite
Cost and Net	64,000,000		64,000,000
Accumulated Amortization	$ 0		$ 0