Indebtedness (Details Textual)	12 Months Ended					1 Months Ended
	Dec. 31, 2012 USD ($)	Dec. 31, 2011 USD ($)	Dec. 31, 2012 6.0% Senior notes due 2013 USD ($)	Dec. 31, 2011 6.0% Senior notes due 2013 USD ($)	Mar. 04, 2008 6.0% Senior notes due 2013 USD ($)	Dec. 31, 2008 6.875% Senior notes due 2018 USD ($)	Dec. 31, 2012 6.875% Senior notes due 2018 USD ($)	Dec. 31, 2011 6.875% Senior notes due 2018 USD ($)	Mar. 04, 2008 6.875% Senior notes due 2018 USD ($)	Dec. 31, 2012 Note payable to Fumedica USD ($)	Dec. 31, 2012 Note payable to Fumedica CHF	Dec. 31, 2011 Note payable to Fumedica USD ($)	Dec. 31, 2011 Note payable to Fumedica CHF	Dec. 31, 2006 Note payable to Fumedica CHF	Dec. 31, 2012 Cambridge Leases USD ($)	Dec. 31, 2011 Cambridge Leases USD ($)
Debt Instrument
Principal amount of senior notes					$ 450,000,000				$ 550,000,000
Interest rate on senior notes					6.00%				6.875%
Redemption percentage par value of senior notes					99.886%				99.184%
Notes redemption condition	100% of the principal amount plus accrued interest and a specified make-whole amount
Percentage of redemption of notes	100.00%
Increased carrying amount of interest rate swap						62,800,000
Interest to be amortized on debt	39,100,000
Senior unsecured revolving credit facility	360,000,000
Borrowings under revolving credit facility	0
Notes payable, line of credit and other financing arrangements	687,396,000	1,060,808,000	0	449,900,000			586,400,000	592,300,000		14,500,000		16,400,000		61,400,000
Present value of notes payable										17,900,000	16,400,000	19,700,000	18,600,000
Remaining obligation of financing arrangements															$ 86,500,000	$ 2,200,000