Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Cash flows from operating activities:
Net income	$ 1,380,033	$ 1,266,686	$ 898,573
Adjustments to reconcile net income to net cash flows from operating activities:
Depreciation and amortization of property, plant and equipment, and intangible assets	365,648	358,933	355,744
Acquired research and development in process	0	0	271,376
Share-based compensation	118,566	113,005	167,826
Fair value adjustment of contingent consideration	27,202	36,065	0
Excess tax benefit from share-based compensation	(54,738)	(50,586)	(13,136)
Deferred income taxes	(116,900)	153,576	(81,410)
Write-down of inventory to net realizeable value	24,821	25,446	11,808
Other	31,537	9,228	10,333
Changes in operating assets and liabilities, net:
Accounts receivable	3,571	(73,374)	(99,227)
Due from unconsolidated joint business	(39,671)	(6,265)	(28,670)
Inventory	(140,309)	(59,219)	(4,527)
Other assets	(27,347)	(43,241)	(12,584)
Accrued expenses and other current liabilities	273,372	33,722	130,875
Other liabilities and taxes payable	34,112	(36,235)	17,692
Net cash flows provided by operating activities	1,879,897	1,727,741	1,624,673
Cash flows from investing activities:
Proceeds from sales and maturities of marketable securities	2,749,558	2,276,720	2,668,694
Purchases of marketable securities	(3,334,434)	(3,696,995)	(1,988,394)
Acquisitions of businesses and variable interest entities, net of cash acquired	(72,401)	(5,000)	(157,428)
Purchases of property, plant and equipment	(254,548)	(208,020)	(173,055)
Proceeds from the sale of strategic investments and long-lived assets	10,058	43,480	0
Purchases of intangible assets	(6,634)	(44,155)	0
Purchases of other investments	(41,941)	(16,324)	(4,492)
Net cash flows used in investing activities	(950,342)	(1,650,294)	345,325
Cash flows from financing activities:
Purchase of treasury stock	(984,715)	(497,975)	(2,077,579)
Proceeds from issuance of stock for share-based compensation arrangements	67,493	314,650	183,486
Excess tax benefit from share-based compensation	54,738	50,586	13,136
Acquisition of noncontrolling interests	0	(148,264)	0
Net distributions to noncontrolling interests	(2,726)	(27,062)	(23,475)
Repayments of borrowings	(2,428)	(11,459)	(18,073)
Cash payments for contingent consideration	(2,500)	0	0
Net proceeds from financing arrangement for the sale of the San Diego facility	0	0	126,980
Other	(7,340)	(338)	10,606
Net cash flows used in financing activities	(877,478)	(319,862)	(1,784,919)
Net decrease in cash and cash equivalents	52,077	(242,415)	185,079
Effect of exchange rate changes on cash and cash equivalents	4,102	(2,641)	(7,370)
Cash and cash equivalents, beginning of the period	514,542	759,598	581,889
Cash and cash equivalents, end of the period	$ 570,721	$ 514,542	$ 759,598