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Collaborative and Other Relationships (Details Textual)
12 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 3 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended
Dec. 31, 2012
USD ($)
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Jan. 31, 2007
Biogen Idec Hemophilia
Mar. 31, 2009
Elan
USD ($)
Sep. 30, 2008
Elan
USD ($)
Dec. 31, 2012
Elan
USD ($)
Dec. 31, 2011
Elan
USD ($)
Dec. 31, 2010
Elan
USD ($)
Sep. 30, 2011
Acorda
USD ($)
Dec. 31, 2012
Acorda
USD ($)
Dec. 31, 2011
Portola Pharmaceuticals
USD ($)
Dec. 31, 2012
Portola Pharmaceuticals
USD ($)
Dec. 31, 2012
AbbVie
USD ($)
Jun. 30, 2011
Genentech
USD ($)
Dec. 31, 2012
Swedish Orphan Biovitrum
USD ($)
Dec. 31, 2012
ISIS Pharmaceuticals
USD ($)
Jun. 30, 2012
ISIS Pharmaceuticals
USD ($)
Jan. 31, 2012
ISIS Pharmaceuticals
USD ($)
Dec. 31, 2012
ISIS Pharmaceuticals
USD ($)
Jun. 30, 2012
ISIS Pharmaceuticals
USD ($)
Mar. 31, 2012
ISIS Pharmaceuticals
USD ($)
Dec. 31, 2012
RITUXAN
USD ($)
Dec. 31, 2011
RITUXAN
Dec. 31, 2010
RITUXAN
Dec. 31, 2012
RITUXAN
Maximum
Dec. 31, 2012
RITUXAN
Minimum
Jun. 30, 2011
RITUXAN
Genentech
USD ($)
Dec. 31, 2012
New Anti-CD20
Dec. 31, 2012
Ocrelizumab
Maximum
Dec. 31, 2012
Ocrelizumab
Minimum
Dec. 31, 2012
GA101
USD ($)
Dec. 31, 2010
GA101
USD ($)
Dec. 31, 2012
GA101
Maximum
Dec. 31, 2012
GA101
Minimum
Feb. 29, 2012
Samsung Biosimilar Agreement
USD ($)
Feb. 29, 2012
Samsung Biosimilar Agreement
KRW
Dec. 31, 2012
Samsung Biosimilar Agreement
USD ($)
Dec. 31, 2012
Samsung Biosimilar Agreement
KRW
Dec. 31, 2012
New Anti-CD20
Third Party Anti CD-20
Roche Group - Genentech
USD ($)
Dec. 31, 2011
New Anti-CD20
Third Party Anti CD-20
Roche Group - Genentech
USD ($)
Dec. 31, 2010
New Anti-CD20
Third Party Anti CD-20
Roche Group - Genentech
USD ($)
Collaborative arrangements and non-collaborative arrangement transactions                                                                                    
Significant Receivables Or Payables Related To Cost Sharing Arrangements With Unconsolidated Variable Interest Entities $ 0 $ 0                                                                                
Investments By Third Party In Joint Venture As Per Agreement.                                                                       250,000,000 280,500,000,000          
Collaborative and Other Relationships (Textual)                                                                                    
Future royalties percentage to be received on sale of ocrelizumab                                                           24.00% 13.50%                      
Percentage of future development and commercialization expenses payable related to GA101                                                               35.00%                    
Profit sharing on sale of GA 101, percentage                                                                   39.00% 35.00%              
Sharing percentage of development expenses of GA 101, Prior to Amendment                                                               30.00%                    
Compensation payment under terms of Amendment for reimbursement of increased share of previously incurred expenses                                                                 10,000,000                  
Percentage of royalties as per collaboration                                                   12.00% 10.00%                              
Royalties to be received under the collaboration agreement                                             10% and 12% on sales of RITUXAN outside the U.S. and Canada, with the royalty period lasting 11 years                                      
Period of collaboration agreement                                             11 years           11 years                          
Royalty period for substantially all of the remaining royalty-bearing sales of RITUXAN in the rest of world                                             expire through 2012                                      
Percentage of Co promotion Operating Profits first fifty million                                             30.00%                                      
Percentage of share of co-promotion profits exceeding $50 million, prior to October 2010 amendment.                                             40.00%                                      
Co-promotion operating profit threshold for Rituxan in U S and Canada to determine share of co promotion operating profit prior to amendment                                             50,000,000                                      
GA101 CLL Sales Trigger - US GA101 gross sales threshold                                                               500,000,000                    
Limit of gross sale of GA 101 to be achieved in preceding 12 months under option one                                                               150,000,000                    
Limit of gross sale of GA 101 to be achieved in any 12 months under option one                                                               150,000,000                    
Limit of gross sale of new product to be achieved in any calendar year under sub option one and two of option two                                             150,000,000                                      
Threshold of gross sales of GA 101 to be achieved in any 12 consecutive months under option two                                             150,000,000                                      
Threshold of gross sales of new product to be achieved in any calendar year under sub option three of option two                                             350,000,000                                      
Estimates of compensatory damages and interest                             125,000,000                                                      
Estimated range of possible loss, related to reduction of share of revenues                                                       50,000,000                            
Percentage of share of Co promotion profits exceeding $50 million                                             40.00% 40.00% 40.00%                                  
Research and development 1,334,919,000 1,219,602,000 1,248,604,000                 36,800,000               30,000,000 12,000,000 29,000,000                                   35,400,000 26,900,000 50,600,000
Milestone payments received under collaboration agreement         50,000,000 75,000,000                                                                        
Milestone payment to be amortized             92,400,000                                                                      
Deferred revenue for the inventory pending shipment of TYSABRI             24,900,000 23,800,000                                                                    
Reimbursements of research and developments expense from Elan             43,700,000 47,500,000 49,800,000                                                                  
Reimbursements of selling general and administrative expenses from Elan             99,900,000 77,300,000 68,500,000                                                                  
Amount reflected in collaboration profit sharing line for collaboration             317,900,000 317,800,000 258,100,000                                                                  
Total milestone payments                   25,000,000                                                                
Expected additional milestone payments for successful achievement of regulatory and commercial sales milestones                     375,000,000   406,800,000                                                          
Expected additional milestone payments when certain sales threshold is met                     15,000,000                                                              
Foreign sales required to trigger milestone                     100,000,000                                                              
Stock acquired in acquisition       100.00%                                                                            
Consideration per product                               10,000,000                                                    
Percentage of reimbursement expenses                               50.00%                                                    
Percentage of development reimbursement expenses                               100.00%                                                    
Reimbursement cost achieving period                               6 years                                                    
Time period for paying remaining balance due                               90 days                                                    
Term for revocation option right                               18 months                                                    
Estimated additional payments upon achievement of development and commercial milestones.                           60,000,000                                                        
Amount paid to purchase Portola equity                       8,200,000                                                            
Payments to Acquire Equity Method Investments                                                                           32,100,000 36,000,000,000      
Remaining obligation of financing arrangements                                                                           12,500,000 13,500,000,000      
Joint Venture Owner Ship Percentage By Third Party.                                                                       85.00% 85.00%          
Equity Method Investments                                                                       45,000,000 49,500,000,000 27,800,000 29,700,000,000      
Percentage of equity interest to the portion of total capital stock                                                                       15.00% 15.00%          
Equity Method Investment Ownership Percentage Maximum                                                                       49.90% 49.90%          
Income (Loss) from Equity Method Investments (4,518,000) 0 0                                                                     (4,500,000)        
Revenues Related To Technical Development And Technology Transfer Services                                                                           13,300,000        
Deferred revenue 148,000,000 69,600,000                                                                       11,200,000        
Additional Milestone Payment                                 10,000,000 59,000,000 45,000,000 10,000,000 59,000,000                                          
Phase Two By Three Milestone Payment                                     18,000,000                                              
License Fee                                 70,000,000 70,000,000 75,000,000                                              
Expected License Fee And Regulatory Milestone Payments                                 $ 148,000,000 $ 130,000,000 $ 150,000,000 $ 148,000,000 $ 130,000,000