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Property, Plant and Equipment (Details) (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2012
Dec. 31, 2011
Sep. 30, 2012
Hillerod, Denmark Facility [Member]
Sep. 30, 2011
Hillerod, Denmark Facility [Member]
Sep. 30, 2012
Hillerod, Denmark Facility [Member]
Sep. 30, 2011
Hillerod, Denmark Facility [Member]
Sep. 30, 2012
Cambridge Leases [Member]
Dec. 31, 2011
Cambridge Leases [Member]
Property, Plant and Equipment [Line Items]                
Land $ 54,000,000 $ 51,900,000            
Buildings 839,700,000 597,900,000            
Leasehold improvements 105,800,000 102,700,000            
Machinery and equipment 824,300,000 570,100,000            
Computer software and hardware 465,900,000 439,700,000            
Furniture and fixtures 43,100,000 37,600,000            
Construction in progress 242,100,000 553,600,000            
Total cost 2,574,900,000 2,353,500,000 454,400,000   454,400,000      
Less: accumulated depreciation (898,300,000) (782,100,000)            
Total property, plant and equipment, net 1,676,583,000 1,571,387,000            
Interest cost capitalization related to large-scale biologic manufacturing facility     6,600,000 8,400,000 23,400,000 24,300,000    
Average estimated useful life         20 years      
Period to complete license to produce commercial product         12 months      
Construction cost incurred not yet paid             56,600,000 2,200,000
Expected charges to vacate building             $ 35,000,000